945663-32-1

Basic information

• Product Name: (E)(4-(4-(3-bromopropoxy)but-2-enyloxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone
• Synonyms: (E)(4-(4-(3-bromopropoxy)but-2-enyloxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone
• CAS NO: 945663-32-1
• Molecular Weight: 439.733
• Mol File: 945663-32-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)(4-(4-(3-bromopropoxy)but-2-enyloxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)(4-(4-(3-bromopropoxy)but-2-enyloxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone(945663-32-1)
• EPA Substance Registry System: (E)(4-(4-(3-bromopropoxy)but-2-enyloxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone(945663-32-1)

Safety Data

• Hazardous Substances Data: 945663-32-1(Hazardous Substances Data)

Upstream product

• 151-10-0 1,3-Dimethoxybenzene 
• 122-01-0 4-chloro-benzoyl chloride 
• 57600-76-7 4-chloro-2',4'-dimethoxybenzophenone 
• 18239-10-6 2,4-dihydroxy-4'-chlorobenzophenone 
• 945663-27-4 (4-(8-bromooctyloxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone 
• 945663-30-9 (E)-(4-(4-bromobut-2-enyloxy)-2-hydroxyphenyl)(4-chlorophenyl)methanone 
• 945663-31-0 (E)-(4-chlorophenyl)(2-hydroxy-4-(4-(3-hydroxypropoxy)but-2-enyloxy)phenyl)methanone 

Relevant articles and documents

Discovery of 1,4-didydroxy-2-naphthoate prenyltransferase inhibitors: New drug leads for multidrug-resistant gram-positive pathogens

Since utilization of menaquinone in the electron transport system is a characteristic of Gram-positive organisms, the 1,4-dihydroxy-2-naphthoate prenyltransferase (MenA) inhibitors 1a and 2a act as selective antibacterial agents against organisms such as methicillin-resistant Stapylococcus aureus (MRSA), Staphylococcus epidermidis (MRSE), and Mycobacterium spp. Growth of drug-resistant Gram-positive organisms was sensitive to the MenA inhibitors, indicating that menaquinone synthesis is a valid new drug target in Gram-positive organisms.