945762-00-5

Basic information

• Product Name: 3-bromo-1H-indazole-7-carbonitrile
• Synonyms: 3-bromo-1H-indazole-7-carbonitrile;1H-INDAZOLE-7-CARBONITRILE, 3-BROMO-
• CAS NO: 945762-00-5
• Molecular Formula: C8H4BrN3
• Molecular Weight: 222.045
• Mol File: 945762-00-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 425.3°C at 760 mmHg
• Flash Point: 211°C
• Appearance: /
• Density: 1.85g/cm³
• Vapor Pressure: 1.94E-07mmHg at 25°C
• Refractive Index: 1.739
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.69±0.40(Predicted)
• CAS DataBase Reference: 3-bromo-1H-indazole-7-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-1H-indazole-7-carbonitrile(945762-00-5)
• EPA Substance Registry System: 3-bromo-1H-indazole-7-carbonitrile(945762-00-5)

Safety Data

• Hazardous Substances Data: 945762-00-5(Hazardous Substances Data)

Usage

General Description

3-bromo-1H-indazole-7-carbonitrile is a chemical compound that belongs to the indazole family. It is a derivative of indazole with a bromine atom and a cyano group attached to its 7th carbon. 3-bromo-1H-indazole-7-carbonitrile is widely used in pharmaceutical research, especially in the development of new drug molecules due to its unique chemical structure and potential pharmacological properties. It has been found to exhibit various biological activities and has potential applications in the synthesis of novel pharmaceuticals and organic compounds. The chemical properties and reactivity of 3-bromo-1H-indazole-7-carbonitrile make it a valuable building block in the synthesis of complex organic molecules and drug discovery.

InChI:InChI=1/C8H4BrN3/c9-8-6-3-1-2-5(4-10)7(6)11-12-8/h1-3H,(H,11,12)

Upstream product

• 256228-64-5 1H-indazole-7-carbonitrile 
• 2942-42-9 7-Nitroindazole 
• 21443-96-9 1H-indazol-7-amine 
• 570-24-1 2-Methyl-6-nitroaniline 
• 945761-94-4 7-iodo-1H-indazole 
• 945761-95-5 3-bromo-7-iodo-1H-indazole 
• 557-21-1 dicyanozinc 

Downstream Products

• 1040101-01-6 C₈H₅BrN₂O₂ 

Relevant articles and documents

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

Efficient synthesis of 7-substituted or 3,7-disubstituted 1H-indazoles

This work reports on the synthesis of the novel indazole scaffolds 7-OTf-1H-indazole (trifluoromethanesulfonic acid 1H-indazol-7-yl ester), 7-iodo-1H-indazole and 3-bromo-7-iodo-1H-indazole. These new compounds are potent building blocks in divergent syntheses of indazoles via palladium cross-coupling reactions. Georg Thieme Verlag Stuttgart.