94609-23-1

Basic information

• Product Name: 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER
• Synonyms: 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER;ETHYL 4,4,4-TRIFLUORO-2-(HYDROXYIMINO)-3-OXOBUTANOATE
• CAS NO: 94609-23-1
• Molecular Formula: C₆H₆F₃NO₄
• Molecular Weight: 213.11
• Mol File: 94609-23-1.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER(94609-23-1)
• EPA Substance Registry System: 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER(94609-23-1)

Safety Data

• Hazardous Substances Data: 94609-23-1(Hazardous Substances Data)

Upstream product

• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 1522-43-6 ethyl 3-oxo-4,4,4-trifluorobutanoate enol 
• 544-16-1 n-Butyl nitrite 

Downstream Products

• 1253196-13-2 ethyl 3-(trifluoromethyl)pyrazine-2-carboxylate 
• 3885-40-3 3-(trifluoromethyl)quinoxaline-2-carboxylic acid ethyl ester 
• 102608-31-1 ethyl 4,4,4-trifluoro-3-hydroxy-2-methoxyiminobutanoate 
• 82874-80-4 ethyl 4,4,4-trifluoro-2-methoxyimino-3-oxobutanoate 

Relevant articles and documents

IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS

The invention provides certain difluorocyclohexyl-imidazopyridazinyl-imidazolidinone compounds of formula II as IL-17A inhibitors, pharmaceutical compositions thereof, and methods of using a compound of formula II to treat certain symptoms of psoriasis, rheumatoid arthritis or multiple sclerosis.

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE

The present invention relates to compounds of Formula (I) inhibiting indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) enzymes. Further, their synthesis and their use as medicaments in inter alia cancer is disclosed.

METHOD FOR THE PREPARATION OF 3-(TRIFLUOROMETHYL)PYRAZINE-2-CARBOXYLIC ACID ESTERS

The invention discloses a method for the preparation of 3-(trifluoromethyl)pyrazine-2-carboxylic acid esters starting from alkyl 4,4,4-trifluoro-2-(hydroxyimino)-3-oxobutanoates by reaction with ethylenediamine.