1253196-13-2Relevant articles and documents
Short and Safe Synthesis of Ethyl 3-(Trifluoromethyl)pyrazine-2-carboxylate
Zaragoza, Florencio,Gantenbein, Annabelle
, p. 448 - 450 (2017)
The treatment of ethyl 2-hydroxyimino-4,4,4-trifluoro-3-oxobutanoate (3) with trialkyl phosphites, ethylenediamine, and an excess of a carboxylic acid in pyridine or picoline leads to the formation of an intermediate, which can be aromatized to a pyrazine by treatment with bromine or other oxidants. This synthesis can be performed either with the isolated oxime 3 or from ethyl 4,4,4-trifluoro-3-oxobutanoate (1) in a one-pot fashion, without any solvent change and without having to isolate any intermediates.
Iodine-containing pyrazinamide compound, preparation method and applications thereof, and bactericide
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Paragraph 0044; 0059-0060, (2019/05/02)
The present invention relates to the field of pesticide bactericides, and discloses an iodine-containing pyrazinamide compound, a preparation method and applications thereof, and a bactericide, wherein the compound has a structure represented by a formula (I). According to the present invention, the iodine-containing pyrazinamide compound with the completely-new structure is designed by introducing the pyrazine ring of NNF-0721 and the diphenyl ether fragment having broad biological activity, and can be used as the completely-new succinate dehydrogenase inhibitor or bactericide. The formula (I) is defined in the specification.
Pyrazinamide compound, preparation method and applications thereof, and bactericide
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, (2019/11/04)
The present invention relates to the field of pesticide bactericides, and discloses a pyrazinamide compound, a preparation method and applications thereof, and a bactericide, wherein the compound hasa structure represented by a formula (I). The preparatio