1253196-13-2

Basic information

• Product Name: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate
• Synonyms: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate;Methyl3-(trifluoroMethyl)pyrazine-2-carboxylate
• CAS NO: 1253196-13-2
• Molecular Formula: C8H7F3N2O2
• Molecular Weight: 220.1485896
• Mol File: 1253196-13-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate(1253196-13-2)
• EPA Substance Registry System: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate(1253196-13-2)

Safety Data

• Hazardous Substances Data: 1253196-13-2(Hazardous Substances Data)

Upstream product

• 94609-23-1 ethyl 4,4,4-trifluoro-2-(hydroxyimino)-3-oxobutanoate 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 107-15-3 ethylenediamine 
• 363-58-6 ethyl 2-chloro-4,4,4-trifluoro-3-oxobutanoate 
• 18299-54-2 ethylenediamine hydrochloride 
• 333-18-6 1,2-diaminoethane dihydrochloride 

Relevant articles and documents

Short and Safe Synthesis of Ethyl 3-(Trifluoromethyl)pyrazine-2-carboxylate

The treatment of ethyl 2-hydroxyimino-4,4,4-trifluoro-3-oxobutanoate (3) with trialkyl phosphites, ethylenediamine, and an excess of a carboxylic acid in pyridine or picoline leads to the formation of an intermediate, which can be aromatized to a pyrazine by treatment with bromine or other oxidants. This synthesis can be performed either with the isolated oxime 3 or from ethyl 4,4,4-trifluoro-3-oxobutanoate (1) in a one-pot fashion, without any solvent change and without having to isolate any intermediates.

Iodine-containing pyrazinamide compound, preparation method and applications thereof, and bactericide

The present invention relates to the field of pesticide bactericides, and discloses an iodine-containing pyrazinamide compound, a preparation method and applications thereof, and a bactericide, wherein the compound has a structure represented by a formula (I). According to the present invention, the iodine-containing pyrazinamide compound with the completely-new structure is designed by introducing the pyrazine ring of NNF-0721 and the diphenyl ether fragment having broad biological activity, and can be used as the completely-new succinate dehydrogenase inhibitor or bactericide. The formula (I) is defined in the specification.

Trifluoromethyl-containing pyrazinamide compound, preparation method and applications thereof, and bactericide

The present invention relates to the field of pesticide bactericides, and discloses a trifluoromethyl-containing pyrazinamide compound, a preparation method and applications thereof, and a bactericide, wherein the compound has a structure represented by a