1253196-13-2

Basic information

• Product Name: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate
• Synonyms: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate;Methyl3-(trifluoroMethyl)pyrazine-2-carboxylate
• CAS NO: 1253196-13-2
• Molecular Formula: C8H7F3N2O2
• Molecular Weight: 220.1485896
• Mol File: 1253196-13-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate(1253196-13-2)
• EPA Substance Registry System: Ethyl 3-(trifluoroMethyl)pyrazine-2-carboxylate(1253196-13-2)

Safety Data

• Hazardous Substances Data: 1253196-13-2(Hazardous Substances Data)

Upstream product

• 107-15-3 ethylenediamine 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 363-58-6 ethyl 2-chloro-4,4,4-trifluoro-3-oxobutanoate 
• 333-18-6 1,2-diaminoethane dihydrochloride 
• 18299-54-2 ethylenediamine hydrochloride 
• 94609-23-1 ethyl 4,4,4-trifluoro-2-(hydroxyimino)-3-oxobutanoate 

Relevant articles and documents

Short and Safe Synthesis of Ethyl 3-(Trifluoromethyl)pyrazine-2-carboxylate

The treatment of ethyl 2-hydroxyimino-4,4,4-trifluoro-3-oxobutanoate (3) with trialkyl phosphites, ethylenediamine, and an excess of a carboxylic acid in pyridine or picoline leads to the formation of an intermediate, which can be aromatized to a pyrazine by treatment with bromine or other oxidants. This synthesis can be performed either with the isolated oxime 3 or from ethyl 4,4,4-trifluoro-3-oxobutanoate (1) in a one-pot fashion, without any solvent change and without having to isolate any intermediates.

Iodine-containing pyrazinamide compound, preparation method and applications thereof, and bactericide

The present invention relates to the field of pesticide bactericides, and discloses an iodine-containing pyrazinamide compound, a preparation method and applications thereof, and a bactericide, wherein the compound has a structure represented by a formula (I). According to the present invention, the iodine-containing pyrazinamide compound with the completely-new structure is designed by introducing the pyrazine ring of NNF-0721 and the diphenyl ether fragment having broad biological activity, and can be used as the completely-new succinate dehydrogenase inhibitor or bactericide. The formula (I) is defined in the specification.

Pyrazinamide compound, preparation method and applications thereof, and bactericide

The present invention relates to the field of pesticide bactericides, and discloses a pyrazinamide compound, a preparation method and applications thereof, and a bactericide, wherein the compound hasa structure represented by a formula (I). The preparatio