94635-25-3

Upstream product

• 94635-24-2 1-(4-methoxyphenyl)piperidin-4-one 
• 105-56-6 ethyl 2-cyanoacetate 
• 110-89-4 piperidine 
• 94635-23-1 ethyl 1-(p-methoxyphenyl)-4-oxo-3-piperidinecarboxylate 
• 104-94-9 4-methoxy-aniline 
• 56525-68-9 3,3'-(4-methoxy-phenylimino)-di-propionic acid diethyl ester 

Downstream Products

• 94635-27-5 2,6-Diamino-5-[1-(4-methoxy-phenyl)-piperidin-4-yl]-pyrimidin-4-ol 
• 94635-22-0 2,4-diamino-6-chloro-5-[1-(4-methoxyphenyl)-4-piperidinyl]pyrimidine 
• 94635-26-4 Cyano-[1-(4-methoxy-phenyl)-piperidin-4-yl]-acetic acid ethyl ester 

Relevant academic research and scientific papers

2,4-diamino-[4-piperidinyl]pyrimidines useful as antibacterial agents, antimalarial agents, antitumors agents

The pyrimidine derivatives of formula I STR1 wherein R1 is naphthyl, substituted naphthyl or substituted phenyl; R2 is hydrogen or lower alkoxy; and A is an optionally present ethylene or 1,3-propylene, and wherein the diaminopyridin

5-(N-Arylnortropan-3-yl)- and 5-(N-Arylpiperidin-4-yl)-2,4-diaminopyrimidines. Novel Inhibitors of Dihydrofolate Reductase

Based on a computer-assisted analysis of the three-dimensional structure of the binary complex of E.coli dihydrofolate reductase (DHFR) with methotrexate, 5-(N-arylnortropan-3-yl)- and 5-(N-arylpiperidin-4-yl)-2,4-diaminopyrimidines 2 and 4 were designed