94636-82-5 Usage
General Description
1,4-Benzenedicarboxylic acid, 2-[(2-carboxyphenyl)amino]-, also known as the drug cariprazine, is a potent and selective dopamine D3/D2 receptor partial agonist with partial agonist activity at the serotonin 5-HT1A receptor. Cariprazine is approved for the treatment of schizophrenia and bipolar disorder in adults. It is also being investigated for the treatment of major depressive disorder and as an adjunctive treatment for the management of negative symptoms in schizophrenia. This chemical is an important tool in the treatment of various psychiatric disorders and has shown promise in improving symptoms and quality of life for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 94636-82-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,6,3 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 94636-82:
(7*9)+(6*4)+(5*6)+(4*3)+(3*6)+(2*8)+(1*2)=165
165 % 10 = 5
So 94636-82-5 is a valid CAS Registry Number.
94636-82-5Relevant articles and documents
Synthesis of Substituted 9-Oxo-9,10-dihydroacridine-4-carboxylic Acids. I. Factors Affecting the Direction of Ring Closure of Substituted N-(2-Carboxyphenylamino)benzoic Acids
Stewart, Georgina M.,Rewcastle, Gordon W.,Denny, William A.
, p. 1939 - 1950 (2007/10/02)
The cyclodehydration of 16 substituted N-(2-carboxyphenylamino)benzoic acids to substituted 9-oxo-9,10-dihydroacridine-4-carboxylic acids with conc.H2SO4, POCl3 and ethyl polyphosphate (epp) has been studied by h.p.l.c.Direction of ring closure can be qua