1967-31-3

Usage

Uses

Due to the limited information available on 2-chloroterephthalic acid, its specific applications are not well-documented. However, based on its chemical structure and the properties of similar compounds, it can be inferred that it may have potential uses in various industries. Some possible applications could include:
Used in Chemical Synthesis:
2-chloroterephthalic acid could be used as a building block or intermediate in the synthesis of more complex organic compounds, such as pharmaceuticals, dyes, or polymers. Its unique structure with a chlorine atom and carboxylic acid groups may provide specific reactivity or properties that are desirable in certain chemical reactions.
Used in Material Science:
2-chloroterephthalic acid may also find applications in the development of new materials, such as plastics, resins, or coatings, where its chemical structure could contribute to desired properties like durability, heat resistance, or chemical stability.
Used in Research and Development:
2-chloroterephthalic acid could be utilized in academic or industrial research settings to explore its potential properties and applications, as well as to investigate its reactivity with other compounds or its behavior under various conditions.

InChI:InChI=1/C8H5ClO4/c9-6-3-4(7(10)11)1-2-5(6)8(12)13/h1-3H,(H,10,11)(H,12,13)

Upstream product

• 5162-82-3 3-chloro-4-methylbenzoic acid 
• 7697-25-8 2-chloro-4-methylbenzoic acid 
• 10388-10-0 2-chloro-1,4-bis-(trichloromethyl)-benzene 
• 99848-93-8 4-ethyl-2-chloro-benzyl chloride 
• 50-84-0 2,4 dichlorobenzoic acid 
• 201230-82-2 carbon monoxide 
• 90649-68-6 1-(2-chloro-4-methylphenyl)ethan-1-one 
• 4395-80-6 2-chloro-1-isopropyl-4-methyl-benzene 
• 7697-37-2 nitric acid 
• 104-82-5 4-Methylbenzyl chloride 
• 1897-47-8 2-Chlor-terephthalonitril 
• 7647-01-0 hydrogenchloride 
• 7722-64-7 potassium permanganate 
• 620-16-6 3-chloroethylbenzene 

Downstream Products

• 18643-84-0 2-chloro-1,4-benzenedicarboxylic acid dimethyl ester 
• 55737-77-4 2-chloro-1,4-benzenedicarboxylic acid,1-methyl ester 
• 13815-87-7 2-chloro-1,4-benzenedicarbonyl dichloride 
• 1980-31-0 chloro-terephthalic acid diamide 
• 70-09-7 2-chloro-N¹,N⁴-bis(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)terephthalamide 
• 120824-92-2 2-chloro-1,4-benzenedicarboxylic acid, 4-(1-methylethyl) ester 

Relevant academic research and scientific papers

Functionalization in flexible porous solids: Effects on the pore opening and the host-guest interactions

The synthesis on the gram scale and characterization of a series of flexible functionalized iron terephthalate MIL-53(Fe) type solids are reported. Chemical groups of various polarities, hydrophilicities, and acidities (-Cl, -Br, -CF3, -CH3, -NH2, -OH, -CO2H) were introduced through the aromatic linker, to systematically modify the pore surface. X-ray powder diffraction (XRPD), molecular simulations, thermogravimetric analyses, and in situ IR and 57Fe Moessbauer spectrometries indicate some similarities with the pristine MIL-53(Fe) solid, with the adoption of the narrow pore form for all solids in both the hydrated and dry forms. Combined XRPD and computational structure determinations allow concluding that the geometry of the pore opening is predominantly correlated with the intraframework interactions rather than the steric hindrance of the substituent. Only (MIL-53(Fe)-(CF3)2) exhibits a nitrogen accessible porosity (SBET ≈ 100 m2 g-1). The adsorption of some liquids leads to pore openings showing some very specific behaviors depending on the guest-MIL-53(Fe) framework interactions, which can be related to the energy difference between the narrow and large pore forms evaluated by molecular simulation.

Microwave-assisted solvothermal synthesis and optical properties of tagged MIL-140A metal-organic frameworks

A series of tagged MIL-140A-R frameworks have been synthesized using a microwave-assisted solvothermal method. Compared with their UiO-66-R polymorphs, the absorption energies in the MIL-140A-R series (R = NH2, NO 2, Br, Cl, and F) are extended toward the visible region because of the spatial arrangement of the linkers.

Preparation method of aromatic dicarboxylic acid derivative

The invention provides a preparation method of an aromatic dicarboxylic acid derivative, wherein the preparation method comprises the following steps: step 1, carrying out a coupling reaction on dihalogenated aromatic hydrocarbon and metal cyanide at a temperature of 40-200 DEG C under metal catalysis in a solvent, and carrying out extraction layering concentration to obtain a dicyano compound after the reaction is finished; and step 2, carrying out a hydrolysis reaction on the obtained dicyanogen compound at the temperature of 60-200 DEG C under an acidic condition, and carrying out post-treatment to obtain the final product. According to the preparation method of the aromatic dicarboxylic acid derivative, dihalogenated aromatic hydrocarbon reacts with metal cyanide and then is hydrolyzedunder the acidic condition to obtain aromatic acid or the derivative thereof, and the preparation method has the remarkable advantages that the raw materials are cheap and easy to obtain, operation is easy and convenient, the yield is high, three wastes are easy to dispose, the product quality is high, and the substrate tolerance is good.

BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING SAME

Provided herein are compounds and methods for modulating abnormal repeat expansions of gene sequences. More particularly, provided are inhibitors of RNA and the uses of such inhibitors in regulating nucleotide repeat expansions, e.g., to treat Myotonic Dystrophy Type 1 (DM1 ), Myotonic Dystrophy Type 2 (DM2), Fuchs dystrophy, Huntington Disease, Amyotrophic Lateral Sclerosis, or Frontotemporal Dementia.

Halogen bonding in UiO-66 frameworks promotes superior chemical warfare agent simulant degradation

Herein, a series of halogenated UiO-66 derivatives was synthesized and analyzed for the breakdown of the chemical warfare agent simulant dimethyl-4-nitrophenyl phosphate (DMNP) to analyze ligand effects. UiO-66-I degrades DMNP at a rate four times faster than the most active previously reported MOFs. MOF defects were quantified and ruled out as a cause for increased activity. Theoretical calculations suggest the enhanced activity of UiO-66-I originates from halogen bonding of the iodine atom to the phosphoester linkage allowing for more rapid hydrolysis of the P-O bond.

Cerium-based metal organic frameworks with UiO-66 architecture: Synthesis, properties and redox catalytic activity

A series of nine Ce(IV)-based metal organic frameworks with the UiO-66 structure containing linker molecules of different sizes and functionalities were obtained under mild synthesis conditions and short reaction times. Thermal and chemical stabilities were determined and a Ce-UiO-66-BDC/TEMPO system was successfully employed for the aerobic oxidation of benzyl alcohol.

Tuning the hydrogenation activity of Pd NPs on Al-MIL-53 by linker modification

The hydrogenation activity of 3 wt.% Pd nanoparticles supported on various mono-group (H, OCH3, NH2, Cl, and NO2) substituted Al-MIL-53 materials has been investigated. Substituents enhanced the dispersion of palladium nanoparticles on Al-MIL-53, leading to a narrow particle size distribution in the range of 2 to 4 nm. Pd nanoparticles on fresh catalysts were present as a mixture of Pd(ii) and Pd(0) with different ratios. These Pd species readily became metallic in a hydrogen flow even at room temperature. Their activities in hydrogenation of phenol and phenylacetylene are linked to the substituents on the aromatic ring of the framework. Catalysts with electron-donating groups (OCH3 and NH2) show much higher activity than those containing electron-withdrawing groups (Cl and NO2). This behavior might be explained by the hydrogen dissociation abilities of metallic Pd nanoparticles affected by the organic linkers.

Single- and mixed-linker Cr-MIL-101 derivatives: A high-throughput investigation

New single- and mixed-linker Cr-MIL-101 derivatives bearing different functional groups have been synthesized. The influence of the reaction parameters, such as metal source (CrO3, CrCl3, and Cr(NO3)3·9H2O) or linker composition, on product formation have been investigated using high-throughput methods. Highly crystalline Cr-MIL-101 materials were obtained with CrCl3 as the metal source with either 2-bromoterephthalic (TA-Br) or 2-nitroterephthalic (TA-NO2) acid as one of the mixed-linker components. On the basis of these results, numerous new mixed-linker Cr-MIL-101 derivatives containing -NH2, -NO2, -H, -SO3H, -Br, -OH, -CH 3, and -COOH have been synthesized. The use of TA-NH2 and TA-OH were shown, under the same reaction conditions, to lead to decarboxylation and the formation of 3-amino- and 3-hydroxybenzoic acid, respectively. Furthermore, we were also able to directly synthesize single-linker Cr-MIL-101-X derivatives with X = F, Cl, Br, CH3. Postsynthetic modification was used to selectively reduce the mixed-linker compound Cr-MIL-101-Br-NO 2 to Cr-MIL-101-Br-NH2. To establish the successful incorporation of the linker molecules and possible decomposition of certain starting materials, 1H NMR spectra of dissolved reaction products were recorded.

USE OF A POROUS CRYSTALLINE HYBRID SOLID AS A NITROGEN OXIDE REDUCTION CATALYST AND DEVICES

The present invention relates to the use of solids consisting of a metal-organic framework (MOF) and having the units of the following formula (I): MmOkXILp as a nitrogen-oxide catalyst. The present invention also relates to devices for enabling the implementation of said use. The nitrogen oxides in question are nitrogen monoxide and nitrogen dioxide, collectively referred to as NOx. The MOF solids of the present invention are advantageously capable of removing nitrogen oxides from a liquid or gaseous effluent, for example from water, from the exhaust gases of a vehicle, factory, workshop, laboratory, stored products, urban air vents, etc., without any reducing agent and at a low temperature. The DeNOx catalysis is a major issue for our societies. The invention can be used for reducing or even avoiding the consequences for public health of the toxic NOx gases resulting from human activity.

POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST

The invention relates to solids made of a porous crystalline metal-organic framework (MOF) loaded with at least one gas of biological interest, and to a method for preparing the same. The MOF solids of the present invention are capable of adsorbing and releasing in a controlled manner gases having a biological interest. They can be used in the pharmaceutical field and/or for applications in the cosmetic field. They can also be used in the food industry.