94654-53-2Relevant academic research and scientific papers
Potential Antitumor Agents. 46. Structure-Activity Relationships for Acridine Monosubstituted Derivatives of the Antitumor Agent N--9-aminoacridine-4-carboxamide
Rewcastle, Gordon W.,Atwell, Graham J.,Chambers, David,Baguley, Bruce C.,Denny, William A.
, p. 472 - 477 (2007/10/02)
A series of monosubstituted derivatives of the new antitumor agent N--9-aminoacridine-4-carboxamide has been prepared, bearing methyl, methoxy, and chloro groups at available acridine positions.The physicochemical properties and an
Synthesis of Substituted 9-Oxo-9,10-dihydroacridine-4-carboxylic Acids. I. Factors Affecting the Direction of Ring Closure of Substituted N-(2-Carboxyphenylamino)benzoic Acids
Stewart, Georgina M.,Rewcastle, Gordon W.,Denny, William A.
, p. 1939 - 1950 (2007/10/02)
The cyclodehydration of 16 substituted N-(2-carboxyphenylamino)benzoic acids to substituted 9-oxo-9,10-dihydroacridine-4-carboxylic acids with conc.H2SO4, POCl3 and ethyl polyphosphate (epp) has been studied by h.p.l.c.Direction of ring closure can be qua
