1-Methyl 2-[(2-carboxyphenyl)amino]-6-methoxybenzoate

Base Information

Chemical Name:1-Methyl 2-[(2-carboxyphenyl)amino]-6-methoxybenzoate
CAS No.:94654-53-2
Molecular Formula:C16H15NO5
Molecular Weight:301.299
Hs Code.:
DSSTox Substance ID:DTXSID501213774

Synonyms:1-Methyl 2-[(2-carboxyphenyl)amino]-6-methoxybenzoate;DTXSID501213774;94654-53-2

Suppliers and Price of 1-Methyl 2-[(2-carboxyphenyl)amino]-6-methoxybenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Methyl 2-[(2-carboxyphenyl)amino]-6-methoxybenzoate

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:301.09502258
Heavy Atom Count:22
Complexity:400

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1C(=O)OC)NC2=CC=CC=C2C(=O)O

Technology Process of 1-Methyl 2-[(2-carboxyphenyl)amino]-6-methoxybenzoate

There total 1 articles about 1-Methyl 2-[(2-carboxyphenyl)amino]-6-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 54166-96-0
methyl 2-amino-6-methoxybenzoate

: 1488-42-2,109545-72-4
Diphenyliodonium-2-carboxylate

: 94654-53-2
N-(3-methoxy-2-methoxycarbonylphenylamino)benzoic acid

Guidance literature:: copper diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 12h;
DOI:10.1055/s-1985-31165

Reference yield:

: 94654-53-2
N-(3-methoxy-2-methoxycarbonylphenylamino)benzoic acid

: 94654-73-6
N-(2-carboxyphenylamino)-6-methoxybenzoic acid

Guidance literature:: With sodium hydroxide; at 100 ℃; for 1h;

Reference yield:

: 94654-53-2
N-(3-methoxy-2-methoxycarbonylphenylamino)benzoic acid

: 100113-21-1
9-Amino-3-methoxy-acridine-4-carboxylic acid (2-dimethylamino-ethyl)-amide

Guidance literature:: Multi-step reaction with 5 steps

1: polyphosphate ester (PPE) / 1 h / 100 °C

2: 2 N ethanol. NaOH / 0.5 h / Heating

3: SOCl₂ / 1 h / Heating

4: CH₂Cl₂ / 0.5 h / 20 °C

5: NH₃(g) / various solvent(s) / 0.25 h / 110 - 120 °C

With sodium hydroxide; thionyl chloride; polyphosphate ester; ammonia; In dichloromethane;
DOI:10.1021/jm00154a008