946585-18-8

Basic information

• Product Name: C₂₆H₃₃ClN₂O₃
• CAS NO: 946585-18-8
• Molecular Weight: 457.013
• Mol File: 946585-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₃ClN₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₃ClN₂O₃(946585-18-8)
• EPA Substance Registry System: C₂₆H₃₃ClN₂O₃(946585-18-8)

Safety Data

• Hazardous Substances Data: 946585-18-8(Hazardous Substances Data)

Upstream product

• 324769-06-4 tert-butyl 3,3-dimethyl-4-oxopiperidine-1-carboxylate 
• 475085-56-4 4-(4-chloro-phenyl)-4-hydroxy-3,3-dimethyl-piperidine-1-carboxylic acid tert-butyl ester 
• 690660-21-0 4-(4-chloro-phenyl)-3,3-dimethyl-piperidin-4-ol 
• 690660-22-1 (S)-4-(4-chlorophenyl)-3,3-dimethylpiperidin-4-ol 
• 946594-20-3 tert-butyl (R)-1-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate 
• 103-82-2 phenylacetic acid 
• 946593-51-7 (R)-2-amino-1-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-methylbutan-1-one hydrochloric acid salt 
• 106-39-8 bromochlorobenzene 

Relevant articles and documents

The discovery of BMS-457, a potent and selective CCR1 antagonist

A series of compounds which exhibited good human CCR1 binding and functional potency was modified resulting in the discovery of a novel series of high affinity, functionally potent antagonists of the CCR1 receptor. Issues of PXR activity, ion-channel pote