946826-76-2

Usage

Uses

Used in Pharmaceutical Synthesis:
(1R,3R)-3-Aminomethyl-cyclopentanol is used as a key building block for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of complex organic molecules that can be used in the development of new drugs.
Used in Organic Chemistry Research:
In the field of organic chemistry, (1R,3R)-3-Aminomethyl-cyclopentanol is used as a versatile compound for research purposes. Its reactivity and the presence of both amino and hydroxyl functional groups make it suitable for studying various chemical reactions and mechanisms.
Used in Chiral Compound Development:
Due to its chiral nature, (1R,3R)-3-Aminomethyl-cyclopentanol is used in the development of chiral compounds, which are essential in many biological and pharmaceutical processes. The ability to control the synthesis of one enantiomer over the other is crucial for creating enantiomerically pure compounds with specific biological activities.
Used in Industrial Applications:
(1R,3R)-3-Aminomethyl-cyclopentanol's unique properties also make it useful in various industrial applications. Its potential use as a precursor in the synthesis of specialty chemicals, materials, or as an intermediate in the production of other valuable compounds highlights its importance in the industry.

Upstream product

• 5732-97-8 2-oxa-bicyclo[2.2.1]heptan-3-one 
• 930-30-3 cyclopent-2-enone 
• 81266-47-9 (+/-)-3-(nitromethyl)cyclopentanone 

Downstream Products

• 1260796-43-7 tert-butyl (3-hydroxycyclopentyl)methylcarbamate 

Relevant academic research and scientific papers

POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS

Described herein is a novel series of multi-fluoro-substituted pyrazolopyrimidine compounds or salts thereof. These compounds are Bruton's tyrosine kinase (BTK) inhibitors. These compounds may possess better BTK inhibition selectivity and pharmacokinetic properties. Disclosed herein are the synthesis methods of these compounds. Disclosed herein are novel synthesis methods of the multi-fluoro-substituted benzophenone and substituted phenoxy benzene. Also disclosed are pharmaceutical compositions comprising the BTK inhibitors described herein. The present invention also relates to pharmaceutical formulations comprising the compounds described herein as active ingredients. The present invention also includes the therapeutic methods by administering the BTK inhibitors and their formulations to treat and inhibit autoimmune disease, hypersensitivity disease, inflammatory diseases and cancer.

On the possibility of carbamate-directed hydroboration. An approach to the asymmetric synthesis of 1-aminocyclopentane-1,3-dicarboxylic acid

Hydroboration (using BH3) of 1-substituted 3-cyclopentenes 3, 9 and 17 and an enantioselective synthesis of the excitatory amino acid 1- aminocyclopentane-1,3-dicarboxylic acid via asymmetric hydroboration [90% de, 45% ee using (+)-IpcBH2] of cyclopentene 17 are described.

Cycloalkyl-one-containing benzenesulphonamides

Cycloalkanol[1,2-b]indole-sulphonamides of the formula STR1 where appropriate in an isomeric form, and their salts are disclosed. These compounds are useful to inhibit platelet aggregation and to antagonize thromboxane A2.