947-82-0

Basic information

• Product Name: 2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one
• Synonyms: 2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one
• CAS NO: 947-82-0
• Molecular Formula: C₁₂H₁₄N₂O
• Molecular Weight: 202.2524
• Mol File: 947-82-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 332.5°Cat760mmHg
• Flash Point: 154.9°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 0.000146mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one(947-82-0)
• EPA Substance Registry System: 2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one(947-82-0)

Safety Data

• Hazardous Substances Data: 947-82-0(Hazardous Substances Data)

Usage

General Description

2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one is a chemical compound that belongs to the class of pyrazolones. It is a yellow crystalline powder with a molecular formula of C13H16N2O and a molecular weight of 216.28 g/mol. 2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one is used in the synthesis of pharmaceuticals and has been studied for its potential antioxidant and anti-inflammatory properties. It is also utilized as a light stabilizer in various industrial applications. However, its precise uses and applications are still being explored, and further research is needed to fully understand its potential benefits and risks.

InChI:InChI=1/C12H14N2O/c1-9-12(2,3)11(15)14(13-9)10-7-5-4-6-8-10/h4-8H,1-3H3

Upstream product

• 597-04-6 ethyl 2,2-dimethyl-3-oxobutanoate 
• 100-63-0 phenylhydrazine 
• 89-25-8 edaravone 
• 74-88-4 methyl iodide 
• 591-50-4 iodobenzene 
• 1543006-30-9 1-([1,1'-biphenyl]-2-yl)-3,4,4-trimethyl-1H-pyrazol-5(4H)-one 
• 22717-40-4 4,4,5-trimethyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 

Downstream Products

• 116436-00-1 3,4-dimethyl-1-phenyl-1H-pyrazole 
• 10252-57-0 3,4,5‐trimethyl‐1‐phenyl‐1H-pyrazole 
• 22717-40-4 4,4,5-trimethyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 
• 13295-22-2 3,4,4-trimethyl-1-phenyl-4,5-dihydro-1H-pyrazole 

Relevant articles and documents

Palladium-catalyzed double C-H activation: One-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones from 5-pyrazolones and aryl iodides

A palladium-catalyzed dual C-H activation to construct C-C/C-N bonds for one-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones is successfully developed. This approach involves using a pyrazolone moiety as an internal directing group for C-H activation, and provides a flexible strategy to access this polycyclic skeleton.

Synthesis and structure-activity relationships of miticidal 4,5- dihydropyrazole-5-thiones

A series of novel 4,5-dihydropyrazole-5-thiones (DHPs) was synthesised by treating the corresponding dihydropyrazolones with Lawesson's reagent and evaluated for miticidal activity against two-spotted spider mites (Tetranychus urticae Koch). Of these, 3-(