947-82-0

Usage

Uses

Used in Pharmaceutical Synthesis:
2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be incorporated into drug molecules, potentially enhancing their therapeutic effects.
Used in Antioxidant Applications:
2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one is used as an antioxidant agent. Its ability to scavenge free radicals and protect cells from oxidative damage makes it a promising candidate for use in health and wellness products, as well as in the development of new pharmaceuticals.
Used in Anti-Inflammatory Applications:
2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one is used as an anti-inflammatory agent. Its potential to reduce inflammation and alleviate pain makes it a valuable component in the development of new medications for the treatment of various inflammatory conditions.
Used as a Light Stabilizer in Industrial Applications:
2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one is used as a light stabilizer in various industrial applications. Its ability to protect materials from degradation caused by exposure to light makes it a valuable additive in the manufacturing of plastics, coatings, and other materials.
Further Research:
While 2,4-Dihydro-4,4,5-trimethyl-2-phenyl-3H-pyrazol-3-one has shown promise in various applications, its precise uses and potential benefits are still being explored. Further research is needed to fully understand its capabilities, optimize its synthesis, and evaluate its safety and efficacy in different contexts.

InChI:InChI=1/C12H14N2O/c1-9-12(2,3)11(15)14(13-9)10-7-5-4-6-8-10/h4-8H,1-3H3

Upstream product

• 22717-40-4 4,4,5-trimethyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 
• 597-04-6 ethyl 2,2-dimethyl-3-oxobutanoate 
• 100-63-0 phenylhydrazine 
• 89-25-8 edaravone 
• 74-88-4 methyl iodide 
• 591-50-4 iodobenzene 
• 1543006-30-9 1-([1,1'-biphenyl]-2-yl)-3,4,4-trimethyl-1H-pyrazol-5(4H)-one 

Downstream Products

• 13295-22-2 3,4,4-trimethyl-1-phenyl-4,5-dihydro-1H-pyrazole 
• 22717-40-4 4,4,5-trimethyl-2-phenyl-2,4-dihydro-pyrazole-3-thione 
• 116436-00-1 3,4-dimethyl-1-phenyl-1H-pyrazole 
• 10252-57-0 3,4,5‐trimethyl‐1‐phenyl‐1H-pyrazole 

Relevant academic research and scientific papers

Palladium-catalyzed double C-H activation: One-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones from 5-pyrazolones and aryl iodides

A palladium-catalyzed dual C-H activation to construct C-C/C-N bonds for one-pot synthesis of benzo[c]pyrazolo[1,2-a]cinnolin-1-ones is successfully developed. This approach involves using a pyrazolone moiety as an internal directing group for C-H activation, and provides a flexible strategy to access this polycyclic skeleton.

Detection and Treatment of Schizophrenia

The present invention provides a method for diagnosing schizophrenia, and a schizophrenia diagnostic reagent or device for use in the method. The present invention further provides a therapeutic or ameliorating agent for schizophrenia, which is effective for the treatment or amelioration of schizophrenia. The therapeutic or ameliorating agent for schizophrenia contains a carbonyl scavenger or a carbonyl-modified protein formation inhibitor as an active ingredient. The method for diagnosing schizophrenia according to the present invention includes measuring at least one parameter in a subject, the parameter being selected from the group consisting of: (1) a genetic abnormality of glyoxalase I gene; (2) the expression level or activity of glyoxalase I in a biological sample; (3) the amount of a carbonyl compound or a carbonyl-modified protein that is a protein modified with the carbonyl compound; and (4) the amount of pyridoxal in a biological sample.

Synthesis and structure-activity relationships of miticidal 4,5- dihydropyrazole-5-thiones

A series of novel 4,5-dihydropyrazole-5-thiones (DHPs) was synthesised by treating the corresponding dihydropyrazolones with Lawesson's reagent and evaluated for miticidal activity against two-spotted spider mites (Tetranychus urticae Koch). Of these, 3-(

A mechanistic study on the electrochemical reduction of 4-(4'-methylarylidene)-5-pyrazolone in nonaqueous medium

Mechanism of electrochemical reduction of 4-(4'-methylarylidene)-5-pyrazolone in 0.1 mol dm-3 tetraethylammonium perchlorate-dimethylformamide was studied by cyclic voltammetry at hanging dropping mercury electrode.The title compound exhibits two diffusion-controlled irreversible mono electronic CV waves.These waves are attributed to the reduction of the 5-cyclic carbonyl group.It is concluded that, each wave follows EC mechanism.The follow-up chemical reaction, C, was suggested to be protonation reaction.The electrode mechanism is proposed and discussed in terms of the molecular structure of the arylidene pyrazolone. Key words: electrochemical reduction / arylidenepyrazolone / cyclic voltammetry / electrode mechanism