947330-97-4Relevant articles and documents
MANUFACTURING METHOD OF LOSARTAN METABOLITE EXP-3174
-
Paragraph 0073-0075; 0079-0081, (2020/09/30)
The present invention provides a manufacturing method capable of manufacturing a losartan metabolite EXP-3174 with high purity and high yield using inexpensive starting materials and under mild reaction conditions. The losartan metabolite EXP-3174 is represented by chemical formula 5.
Imidazole-5-Carboxylic Acid Derivatives, The Preparation Method Therefor and The Uses Thereof
-
Page/Page column 9, (2009/04/24)
The invention discloses imidazole-5-carboxylic acid derivatives, and their preparation methods. The derivatives of the invention are Angiotensin II receptor antagonists with angiotensin II antagonistic activity and antihypertensive activity, and thereby can be used as a therapeutical agent to treat hypertension.