94825-57-7 Usage
Uses
Used in Immunocomplex Kinetic Assay:
TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT is used as a research tool for immunocomplex kinetic assays, specifically to determine the activation of p70s6k by DADLE in cell clones D2 and DOE, as well as in non-transfected parental Rat-1 fibroblasts. This helps researchers understand the underlying mechanisms of opioid peptide action and their potential applications in various biological processes.
Used in Analgesic Effect Assessment:
In the field of pain research, TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT is used to assess the analgesic effect of WIN55,212-2 in mice. This allows researchers to evaluate the efficacy of potential pain-relief drugs and their interactions with opioid receptors, contributing to the development of novel therapeutic agents for pain management.
Biochem/physiol Actions
[D-Ala2, D-Leu5]-Enkephalin can induce hibernation in ground squirrels, during summers, when they do not normally hibernate. In multiorgan block preparation, it can prolong the survival time of organs such as, heart, lung, liver, spleen and kidney, up to 46hrs. It aids in tolerance development of myocardium to ischemia. It might have tissue protective role in central nervous system. It prevents and reverses methamphetamine (METH)-induced damage of dopaminergic terminals of brain. It prevents naltrexone-sensitive PC12 cell apoptosis in serum deprivation conditions. Thus, it might play an essential role in the survival of neurons and organs.
Check Digit Verification of cas no
The CAS Registry Mumber 94825-57-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,8,2 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 94825-57:
(7*9)+(6*4)+(5*8)+(4*2)+(3*5)+(2*5)+(1*7)=167
167 % 10 = 7
So 94825-57-7 is a valid CAS Registry Number.
