948314-83-8

Upstream product

• 69729-07-3 H-Gly-Gly-Phe-Leu-OBzl 
• 69729-14-2 benzyl ester of N-tert-butoxycarbonylglycylglycylphenylalanylleucine 
• 73994-89-5 (S)-benzyl 2-((S)-2-(2-aminoacetamido)-3-phenylpropanamido)-4-methylpentanoate 
• 73994-88-4 Boc-Gly-Phe-Leu-OBzl 
• 63649-15-0 L-phenylalanyl-L-leucine benzyl ester 
• 74193-68-3 N-tert-butyloxycarbonyl-L-phenylalanyl-L-leucine benzyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 1738-77-8 L-leucine benzyl ester p-toluenesulfonate 
• 77511-32-1 5>-enkephalin 
• 66891-32-5 HCl_.H-Gly-Gly-Phe-Leu-OBzl 
• 64963-27-5 N-tert-butyloxycarbonyl-L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucine 

Relevant academic research and scientific papers

Method of producing peptide

The present invention is related to a method of producing a peptide, characterized in contacting a reaction mixture with a base after a condensation reaction to hydrolyze while a basic condition is maintained until a ratio of a remaining unreacted active

N-Hydroxy Amides. III. Active Esters of Polystyrene-bound 1-Hydroxy-2-pyrrolidinone and Their Use in Peptide Synthesis

A polymer-bond cyclic N-hydroxy amide has been prepared by reaction of aminomethylated copoly(styrene-2percent divinylbenzene) with 1-hydroxy-5-oxo-3-pyrrolidinecarboxylic acid using dicyclohexylcarbodiimide (DCC) as a condensing agent.Several N-blocked α-amino acids have been loaded on this resin by use of DCC.The amino acid resin can be utilized for peptide synthesis.Repetitive usage of the resin in the form of esters and facile synthesis of a biologically active pentapeptide, Leu5-enkephalin, show the usefulness of the polymer-bound 1-hydroxy-2-pyrrolidinone.