948349-72-2

Upstream product

• 948349-71-1 3-(2-ethoxymethyl-4-hydroxymethyl-phenyl)-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 948350-14-9 3-[4-(4,6-dimethyl-3-p-tolyl-pyrazolo[4,3-c]pyridin-1-ylmethyl)-2-ethoxymethyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948350-19-4 3-[4-(4,6-dimethyl-3-thiophene-2-yl-pyrazolo[4,3-c]pyridin-1-ylmethyl)-2-ethoxymethyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948350-26-3 3-{4-[3-(3,5-dimethyl-pyrazol-1-ylmethyl)-4,6-dimethyl-pyrazolo[4,3-c]pyridin-1-ylmethyl]-2-ethoxymethyl-phenyl}-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948350-55-8 3-[2-ethoxymethyl-4-(6-ethyl-4-methyl-3-thiophen-2-yl-pyrazolo[4,3-c]pyridin-1-ylmethyl)-phenyl]-5-methyl-thiophene-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948350-61-6 3-{2-ethoxymethyl-4-[6-ethyl-3-(4-methoxy-phenyl)-4-methyl-pyrazolo[4,3-c]pyridin-1-ylmethyl]-phenyl}-5-methyl-thiophene-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 1214260-65-7 3-[2-ethoxymethyl-4-(6-ethyl-4-methyl-3-phenyl-pyrazolo[4,3-c]pyridine-1-ylmethyl)-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948349-92-6 3-[2-ethoxymethyl-4-(6-ethyl-3,4-dimethyl-pyrazolo[4,3-c]pyridine-1-ylmethyl)-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948350-09-2 3-[4-(3-acetyl-2,6-dimethyl-pyridine-4-yloxymethyl)-2-ethoxymethyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948350-07-0 3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-ethoxymethyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 
• 948349-73-3 3-[4-(2-butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-yl-methyl)-2-ethoxymethyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-amide 

Relevant academic research and scientific papers

NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE AT1 AND ETA RECEPTORS

The present invention relates to new compounds of the formula [Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, and R31 are as specified herein. The invention also relates to a method for preparation thereof, as well as combinations of the new compounds with previously known agents. The invention also relates to the use of the above-mentioned compounds and combinations for the preparation of a medicament for treating hypertension of different kinds, alleviating organ damage of different kinds, treating or preventing diabetic nephropathy, treating endothelin and angiotensin mediated disorders, and treating prostate cancer.