94849-38-4

Upstream product

• 3061-95-8 D-Ala-Phe-OH 
• 20866-56-2 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)-L-tyrosinate 
• 1668-10-6 glycinamide hydrochloride 
• 3978-80-1 Boc-Tyr-OH 
• 35661-40-6 N-Fmoc L-Phe 
• 35661-38-2 N-(9-fluorenylmethoxycarbonyl)-D-alanine 
• 94883-19-9 D-(N-tert-butoxycarbonylalanyl)-L-phenylalanine 
• 63-91-2 L-phenylalanine 

Downstream Products

• 1027166-82-0 ((S)-2-{(S)-2-[(S)-2-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-3-carbamoyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyrylamino)-acetic acid ethyl ester 
• 1025956-29-9 C₄₆H₆₈N₈O₁₂ 
• 1026283-37-3 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{[(S)-1-((S)-1-carbamoyl-2-methyl-propylcarbamoyl)-2-methyl-propylcarbamoyl]-methyl}-succinamic acid tert-butyl ester 
• 1027906-73-5 C₄₈H₇₁N₇O₁₃ 
• 1025831-19-9 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid benzyl ester 
• 1025941-24-5 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid tert-butyl ester 
• 174077-46-4 [(S)-1-{(R)-1-[(S)-1-(1-{(S)-1-[(S)-1-(Carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-cyclopentylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 132125-59-8 H-Tyr-D-Ala-Phe-Val-Val-Asp-Gly-NH₂ 
• 132125-58-7 H-Tyr-D-Ala-Phe-Val-Asp-Val-Gly-NH₂ 
• 132103-70-9 H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-OH 
• 122752-15-2 deltorphin C 
• 131152-66-4 H-Tyr-D-Ala-Phe-Gly-Val-Val-Asp-NH₂ 

Relevant academic research and scientific papers

Opioid Tripeptides Hybridized with trans-1-Cinnamylpiperazine as Proliferation Inhibitors of Pancreatic Cancer Cells in Two- and Three-Dimensional in vitro Models

According to the World Health Organization, the mortality rate among patients with pancreatic cancer will increase in the upcoming years. Gemcitabine is the first choice for treatment of pancreatic malignancy, but increasing resistance to this drug is dec

Kinetically controlled peptide synthesis mediated by papain using the carbamoylmethyl ester as an acyl donor

A series of dipeptides were synthesized generally in good yields with carbamoylmethyl (Cam) esters as acyl donors in the presence of a cysteine protease, papain, immobilized on Celite. Several segment condensations were also achieved generally in high yields without danger of racemization and formation of the secondary-hydrolysis product. Moreover, partial sequences of some bioactive peptides were prepared through segment condensations, and aimed-at peptides were obtained generally in high yields without the racemization of C-terminal residues of the carboxyl components. Thus, the superiority of the Cam ester in the kinetically controlled peptide synthesis was once again ascertained in couplings mediated by the cysteine protease as in those catalyzed by the serine proteases reported earlier.

Unique sequence in deltorphin C confers structural requirement for δ opioid receptor selectivity

A series of deltorphin C (H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2) analogues were synthesized to assess the consequences of changing anionic and hydrophobic residues on δ receptor selectivity.Analogues with altered C-terminal groups, inverted sequences, or es