948717-18-8

Basic information

• Product Name: 2,4-difluoro-N-methylbenzamide
• Synonyms: 2,4-difluoro-N-methylbenzamide
• CAS NO: 948717-18-8
• Molecular Weight: 171.146
• Mol File: 948717-18-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 228.0±30.0 °C(Predicted)
• Density: 1.238±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2,4-difluoro-N-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-difluoro-N-methylbenzamide(948717-18-8)
• EPA Substance Registry System: 2,4-difluoro-N-methylbenzamide(948717-18-8)

Safety Data

• Hazardous Substances Data: 948717-18-8(Hazardous Substances Data)

Upstream product

• 72482-64-5 2,4-difluorobenzoyl chloride 
• 74-89-5 methylamine 
• 1583-58-0 2,4-difluoro-benzoic acid 

Downstream Products

• 956104-46-4 2-fluoro-4-(4-methoxybenzylamino)-N-methylbenzamide 
• 1209468-29-0 C₁₃H₁₇FN₂O 
• 1209468-37-0 C₁₃H₁₇FN₂O 
• 1233541-56-4 4-fluoro-N-methyl-2-phenoxybenzamide 
• 1233541-59-7 C₁₄H₁₂FNOS 
• 1233541-61-1 C₁₄H₁₂FNOS 
• 1233541-65-5 C₂₀H₁₇NOS₂ 
• 1351185-58-4 2-[3-fluoro-4-(methylcarbamoyl)phenylamino]propionic acid 
• 915087-26-2 4-(1-cyano-cyclobutanylamino)-2-fluoro-N-methyl-benzamide 
• 956104-40-8 ARN-509 
• 915087-25-1 2-fluoro-N-methyl-4-amino-benzamide 

Relevant articles and documents

NEW SUBSTITUTED CYANOINDOLINE DERIVATIVES AS NIK INHIBITORS

The present invention relates to pharmaceutical agents of formula (I) useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF- KB-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.

Substituted diazaspiroalkanes as androgen receptor modulators

This invention provides for compounds of the Formula II: wherein A, B, Het, R1, R2 and R3 are as described herein. These compounds are androgen receptor modulators useful for the treatment of androgen receptor-associated conditions.

SYNTHESIS OF THIOHYDANTOINS

A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52.