948845-91-8

Upstream product

• 948846-69-3 ethyl (3aR,6aR)-1-[4'-(6-oxopyridazin-1(6H)-yl)-1,1'-biphenyl-4-yl]hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate 
• 948846-68-2 ethyl (3aR,6aR)-1-(4'-bromo-1,1'-biphenyl-4-yl)hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate 
• 948846-55-7 ethyl 1-((R)-1-phenyl-ethyl)-hexahydro-1H-pyrrolo[2,3-c]pyrrole-5-carboxylate 
• 948846-39-7 ethyl (3aR,6aR)-hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate 
• 132414-79-0 ethyl hexahydro-1H-pyrrolo[2,3-c]pyrrole-5-carboxylate 
• 504-30-3 2H-Pyridazin-3-one 
• 50-00-0 formaldehyd 
• 948846-70-6 2-{4'-[(3aR,6aR)-hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl]-1,1'-biphenyl-4-yl}pyridazin-3(2H)-one 

Downstream Products

• 1131686-08-2 (3aR,5R,6aR)-5-methyl-1-(4'-(6-oxopyridazin-1(6H)-yl)biphenyl-4-yl)octahydropyrrolo[3,4-b]pyrrole 5-oxide 
• 1131686-10-6 (3aR,5S,6aR)-5-methyl-1-(4'-(6-oxopyridazin-1(6H)-yl)biphenyl-4-yl)octahydropyrrolo[3,4-b]pyrrole 5-oxide 

Relevant academic research and scientific papers

OCTAHYDRO-PYRROLO[3,4-B]PYRROLE N-OXIDES

The invention relates to octahydro-pyrrolo[3,4-b]pyrrole N-oxides as prodrugs of CNS-active compounds, compositions comprising such compounds, methods for making the compounds, salts, and polymorphs, and methods of treating conditions and disorders using

DETERMINATION OF HISTAMINE-3 BIOACTIVITY

The invention relates to an in vivo method for determining the bioactivity of chemical compounds as histamine-3 receptor (H3R) ligands, and provides animal models to determine such bioactivity. The invention further relates to methods for scree

OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES

Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making th