948846-56-8

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 370880-16-3 tert-butyl (3aS,6aS)-octahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate 
• 370880-09-4 (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-1-carboxylic acid tert-butyl ester 

Downstream Products

• 948846-58-0 (3aR,6aR)-1-(4'-cyano-biphenyl-4-yl)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester 
• 948846-59-1 (3aR,6aR)-4'-(octahydro-pyrrolo[3,4-b]pyrrol-1-yl)-biphenyl-4-carbonitrile 
• 948846-57-9 (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Macrocyclic Spiro Pyrimidine Derivatives

Macrocyclic spiro pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions, and disorders using such compounds and compositions are described herein.

Design of a new histamine H3 receptor antagonist chemotype: (3aR,6aR)-5-alkyl-1-aryl-octahydropyrrolo[3,4-b]pyrroles, synthesis, and structure-activity relationships

A new histamine H3 receptor (H3R) antagonist chemotype 1 was designed by combining key pharmacophoric elements from two different precursor structural series and then simplifying and optimizing the resulting combined structural featu

MACROCYCLIC BENZOFUSED PYRIMIDINE DERIVATIVES

Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.

OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES

Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making th