948846-58-0

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 370880-09-4 (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-1-carboxylic acid tert-butyl ester 
• 948846-56-8 (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-1,5-dicarboxylic acid 5-benzyl ester 1-tert-butyl ester 
• 19812-93-2 4-Cyano-4'-hydroxybiphenyl 
• 948846-57-9 (3aR,6aR)-octahydro-pyrrolo[3,4-b]pyrrole-5-carboxylic acid benzyl ester 
• 125261-34-9 trifluoro-methanesulfonic acid 4'-cyano-biphenyl-4-yl ester 

Downstream Products

• 948846-59-1 (3aR,6aR)-4'-(octahydro-pyrrolo[3,4-b]pyrrol-1-yl)-biphenyl-4-carbonitrile 

Relevant academic research and scientific papers

Design of a new histamine H3 receptor antagonist chemotype: (3aR,6aR)-5-alkyl-1-aryl-octahydropyrrolo[3,4-b]pyrroles, synthesis, and structure-activity relationships

A new histamine H3 receptor (H3R) antagonist chemotype 1 was designed by combining key pharmacophoric elements from two different precursor structural series and then simplifying and optimizing the resulting combined structural featu

OCTAHYDRO-PYRROLO[3,4-B]PYRROLE DERIVATIVES

Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making th