948853-03-0Relevant academic research and scientific papers
Organocatalytic asymmetric mannich reactions with JV-Boc and JV-Cbz protected α-amido sulfones (Boc: Tert-butoxycarbonyl, Cbz: Benzyloxycarbonyl)
Marianacci, Olindo,Micheletti, Gabriele,Bernardi, Luca,Fini, Francesco,Fochi, Mariafrancesca,Pettersen, Daniel,Sgarzani, Valentina,Ricci, Alfredo
, p. 8338 - 8351 (2007)
Different malonates and βketoesters can react with N-tert-butoxycarbonyl- (N-Boc) and N-benzyloxycarbonyl- (N-Cbz) protected α-amido sulfones in an organocatalytic asymmetric Mannich-type reaction. The reaction makes use of a simple and easily obtained ph
Phase-transfer-catalyzed enantioselective Mannich reaction of malonates with α-amido sulfones
Fini, Francesco,Bernardi, Luca,Herrera, Raquel P.,Pettersen, Daniel,Ricci, Alfrede,Sgarzani, Valentina
, p. 2043 - 2046 (2007/10/03)
The highly enantioselective reaction between in situ generated, Cbz-protected azomethines and malonates in the presence of 150 mol% of potassium carbonate (50% w/w) and 1 mol% of quinine-derived quaternary ammonium bromides as phase-transfer organocatalys
