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1-(2,6-difluorobenzoyl)piperidin-4-one is a chemical compound with the molecular formula C14H13F2NO2. It is a piperidinone derivative featuring a difluorobenzoyl group attached to the piperidine ring. 1-(2,6-difluorobenzoyl)piperidin-4-one has garnered attention for its potential pharmaceutical properties, such as acting as a selective serotonin reuptake inhibitor (SSRI) and its possible application in treating psychiatric disorders. Additionally, it has been explored as an intermediate in the synthesis of other pharmaceutical compounds, making it a significant molecule for research and development within the pharmaceutical industry.

948853-53-0

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948853-53-0 Usage

Uses

Used in Pharmaceutical Industry:
1-(2,6-difluorobenzoyl)piperidin-4-one is used as a pharmaceutical compound for its potential role as a selective serotonin reuptake inhibitor (SSRI). Its application aims to address psychiatric disorders by modulating serotonin levels in the brain, thereby potentially improving the symptoms and management of these conditions.
Used in Chemical Synthesis:
1-(2,6-difluorobenzoyl)piperidin-4-one is also used as an intermediate in the synthesis of other pharmaceutical compounds. Its unique chemical structure and properties make it a valuable building block for creating novel molecules with potential therapeutic applications, further contributing to the advancement of the pharmaceutical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 948853-53-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,8,8,5 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 948853-53:
(8*9)+(7*4)+(6*8)+(5*8)+(4*5)+(3*3)+(2*5)+(1*3)=230
230 % 10 = 0
So 948853-53-0 is a valid CAS Registry Number.

948853-53-0Relevant academic research and scientific papers

HETEROBICYCLIC COMPOUNDS USEFUL AS KINASE INHIBITORS

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Page/Page column 40, (2008/12/08)

A compound of Formula (I) and enantiomers, diastereomers and pharmaceutically-acceptable salts thereof. Also disclosed are pharmaceutical compositions containing compounds of Formula I, and methods of treating conditions associated with the activity of p3

Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists

Pegurier, Cecile,Collart, Philippe,Danhaive, Pierre,Defays, Sabine,Gillard, Michel,Gilson, Frederic,Kogej, Thierry,Pasau, Patrick,Van Houtvin, Nathalie,Van Thuyne, Marc,van Keulen, BerendJan

, p. 4228 - 4231 (2008/02/09)

The discovery and optimization of a novel class of potent CCR3 antagonists is described. Details of synthesis and SAR are given together with some ADME properties of selected compounds. An optimal balance between activities, physicochemical properties, and in vitro metabolic stability was reached by the proper choice of substituents.

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