948862-69-9Relevant academic research and scientific papers
Organocatalytic asymmetric multi-component [C+NC+CC] synthesis of highly functionalized pyrrolidine derivatives
Ibrahem, Ismail,Rios, Ramon,Vesely, Jan,Córdova, Armando
, p. 6252 - 6257 (2007)
The highly chemo- and enantioselective organocatalytic [C+NC+CC] coupling process between aldehydes, dialkyl 2-aminomalonates and α,β-unsaturated aldehydes is presented. The reaction gives access to highly functionalized pyrrolidine derivatives in good yi
Organocatalytic enantioselective [3+2] cycloaddition of azomethine ylides and α,β-unsaturated aldehydes
Vicario, Jose L.,Reboredo, Silvia,Badia, Dolores,Carrillo, Luisa
, p. 5168 - 5170 (2008/03/18)
(Chemical Equation Presented) One out of a possible 16: Commercially available α,α-diphenylprolinol catalyzes the [3+2] cycloaddition of α,β-unsaturated aldehydes with azomethine ylides derived from imines to produce pyrrolidines as single regioisomers wi
