949161-93-7

Upstream product

• 838-42-6 5,5-dimethyl-2-(4-nitro-phenyl)-[1,3]dioxane 
• 105114-53-2 1-bromo-4-(5,5-dimethyl-1,3-dioxan-2-yl)benzene 
• 107708-70-3 4-(4,4-dimethyl-2,6-dioxacyclohexyl)aniline 
• 555-16-8 4-nitrobenzaldehdye 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 

Downstream Products

• 101420-88-6 4-iodo-3-nitrobenzaldehyde 
• 949162-01-0 (S)-3-[3'-tert-butoxycarbonylamino-4'-iodo-(E)-cinnamoyl]-4-phenyloxazolidin-2-one 
• 949161-92-6 (S)-3-[3'-amino-4'-iodo-(E)-cinnamoyl]-4-phenyloxazolidin-2-one 
• 949162-00-9 (E)-3'-tert-butoxycarbonylamino-4'-iodocinnamic acid 
• 949161-98-2 methyl (E)-3'-tert-butoxycarbonylamino-4'-iodocinnamate 
• 949161-94-8 methyl (E)-3'-nitro-4'-iodocinnamate 
• 949161-95-9 methyl (E)-3'-amino-4'-iodocinnamate 
• 15164-44-0 p-(iodophenyl)carboxaldehyde 

Relevant academic research and scientific papers

Preparation of the central tryptophan moiety of the celogentin/moroidin family of anti-mitotic cyclic peptides

The central functionalized tryptophan core of the celogentin/moroidin family of cyclic peptides has been prepared. The strategy incorporates a novel preparation of 4-iodobenzaldehyde and employs a Larock annulation as the key step. CSIRO 2006.

Cheap and easy synthesis of highly functionalized (het)aryl iodides via the aromatic finkelstein reaction

Aryl iodides are superior coupling partners in cross-couplingA- reactions compared to the corresponding chlorides or bromides. Unfortunately, the iodides are much more expensive, if commercially available at all, than the other halides. Thus, it is often mandatory to transform the available bromides into the corresponding iodides. The copper-catalyzed aromatic Finkelstein reaction turned out to be the method of choice to prepare a number of highly functionalized iodo(het)aryls, including pyridines, 2,2′-bipyridines, and chiral compounds. Georg Thieme Verlag Stuttgart? New York.