94920-90-8Relevant academic research and scientific papers
Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5negative allosteric modulation
Gómez-Santacana, Xavier,Dalton, James A.R.,Rovira, Xavier,Pin, Jean Philippe,Goudet, Cyril,Gorostiza, Pau,Giraldo, Jesús,Llebaria, Amadeu
, p. 567 - 576 (2017/01/28)
Modulation of metabotropic glutamate receptor 5 (mGlu5) with partial allosteric antagonists has received increased interest due to their favourable in?vivo activity profiles compared to the unfavourable side-effects of full inverse agonists. He
Palladium-poly(3-aminoquinoline) hollow-sphere composite: Application in sonogashira coupling reactions
UlIslam, Rafique,Mahato, Sanjit K.,Shukla, Sudheesh K.,Witcomb, Michael J.,Mallick, Kaushik
, p. 2453 - 2461 (2013/08/23)
We report on the use of palladium acetate for the synthesis of a palladium-based polymer composite material as a catalyst for Sonogashira cross-coupling reactions for aryl and heteroaryl of iodides and bromides.
N- (4 -QUINOLINYLMETHYL) SULFONAMIDE DERIVATIVES AND THEIR USE AS ANTHELMINTICS
-
Page/Page column 44, (2013/06/27)
Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein (1), Q, A, R1, R2, R3 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for treating helminth infections comprising administration to an animal a parasiticidally effective amount of a compound or a composition of the invention.
Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2- ethanediones: Potent, selective carboxylesterase inhibitors
Young, Brandon M.,Hyatt, Janice L.,Bouck, David C.,Chen, Taosheng,Hanumesh, Parimala,Price, Jeanine,Boyd, Vincent A.,Potter, Philip M.,Webb, Thomas R.
supporting information; experimental part, p. 8709 - 8715 (2011/02/23)
Inhibition of intestinal carboxylesterases may allow modification of the pharmacokinetics/pharmacodynamic profile of existing drugs by altering half-life or toxicity. Since previously identified diarylethane-1,2-dione inhibitors are decidedly hydrophobic,
