949468-94-4

Basic information

• Product Name: 3-CHLORO-6-(2-METHOXYPHENYL)-PYRIDAZINE
• Synonyms: 3-CHLORO-6-(2-METHOXYPHENYL)-PYRIDAZINE
• CAS NO: 949468-94-4
• Molecular Formula: C₁₁H₉ClN₂O
• Molecular Weight: 220.65
• Mol File: 949468-94-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-CHLORO-6-(2-METHOXYPHENYL)-PYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-6-(2-METHOXYPHENYL)-PYRIDAZINE(949468-94-4)
• EPA Substance Registry System: 3-CHLORO-6-(2-METHOXYPHENYL)-PYRIDAZINE(949468-94-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 949468-94-4(Hazardous Substances Data)

Upstream product

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Relevant articles and documents

Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives

Novel 3,6-disubstituted pyridazines were synthesized by facile method and screened for their vasorelaxant properties utilizing isolated thoracic rat aortic rings. Compounds 8a and 11a exerted potent vasorelaxant activity (IC50 = 198 and 177 μM, respectively) relative to doxazosin mesylate (used reference standard, IC50 = 226 μM), that, they may represent promising hits for treatment of cardiovascular disorders. The observed activity was validated by a statistically significant QSAR model (N = 32, n = 6, R2 = 0.811782, R2cvOO = 0.7153, R2cvMO = 0.7209, F = 17.9708, s2 = 9.65226 × 10-8) that was obtained employing CODESSA-Pro software.