949489-20-7Relevant academic research and scientific papers
Synthesis and immunological evaluation ofN-acyl modified Globo H derivatives as anticancer vaccine candidates
Song, Chengcheng,Ye, Xin-Shan,Zhai, Canjia,Zheng, Xiu-Jing
, p. 1239 - 1243 (2021/09/10)
Globo H is a tumor-associated carbohydrate antigen (TACA), which serves as a valuable target for antitumor vaccine or cancer immunotherapies. However, most TACAs are T-cell-independent, and they cannot induce powerful immune response due to their poor imm
Multi-component one-pot synthesis of the tumor-associated carbohydrate antigen globo-H based on preactivation of thioglycosyl donors
Wang, Zhen,Zhou, Luyuan,El-Boubbou, Kheireddine,Ye, Xin-Shan,Huang, Xuefei
, p. 6409 - 6420 (2008/02/10)
(Chemical Equation Presented) Two efficient routes for the rapid assembly of the tumor-associated carbohydrate antigen Globo-H hexasaccharide 2 by a preactivation based iterative one-pot strategy are reported. The first method involves the sequential coup
