94956-84-0

Basic information

• Product Name: 1,4-Butanediol, 3-methylene-1-phenyl-, 4-acetate
• CAS NO: 94956-84-0
• Molecular Formula: C13H16O3
• Molecular Weight: 220.268
• Mol File: 94956-84-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,4-Butanediol, 3-methylene-1-phenyl-, 4-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Butanediol, 3-methylene-1-phenyl-, 4-acetate(94956-84-0)
• EPA Substance Registry System: 1,4-Butanediol, 3-methylene-1-phenyl-, 4-acetate(94956-84-0)

Safety Data

• Hazardous Substances Data: 94956-84-0(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 100-52-7 benzaldehyde 
• 513-42-8 3-hydroxy-2-methyl-1-propene 
• 94956-83-9 <2-(acetoxymethyl)-3-allyl>tri-n-butylstannane 

Downstream Products

• 1314808-83-7 C₁₉H₃₀O₃Si 
• 1314808-85-9 C₁₇H₂₇BrOSi 
• 1314808-84-8 C₁₇H₂₈O₂Si 
• 1314808-88-2 (E)-9-(tert-butyldimethylsilyloxy)-2,2-dimethyl-7-methylene-9-phenylnon-4-en-3-one 
• 80997-79-1 2-phenyl-4-methylenetetrahydrofuran 

Relevant articles and documents

Synthesis of 2,6-cis-disubstituted 4-methylenetetrahydropyrans by oxy-Michael addition

The combination of an 'ene' reaction between a 2-(2-trialkylsilyloxyalkyl) prop-2-enyl(trimethyl)silane and an alk-1-yn-3-one mediated by zinc(II) iodide, and an intramolecular oxy-Michael reaction, provides an efficient synthesis of cis-2,6-disubstituted 4-methylenetetrahydropyrans of interest in the context of a synthesis of bryostatins. The stereoselective formation of (E)-vinylsilanes in the 'ene' reaction is of interest.