949587-97-7

Upstream product

• 951387-14-7 1-(4-bromophenyl)prop-2-yn-1-amine 
• 100-44-7 benzyl chloride 
• 688362-46-1 N-(1-(4-bromophenyl)prop-2-yn-1-yl)acetamide 
• 85020-75-3 1-(4-bromophenyl)-2-propyn-1-ol 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 1158914-74-9 C₁₉H₁₆BrN₅ 

Relevant academic research and scientific papers

Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis

A series of novel enantiomerically pure azole derivatives was synthesized. The new compounds, bearing both an imidazole as well as a triazole moiety, were evaluated as antimycobacterial agents. One of them proved to have activity against Mycobaterium tube

Synthesis of enantiomerically pure α-[4-(1-substituted)-1,2,3-triazol-4-yl]-benzylacetamides via microwave-assisted click chemistry: towards new potential antimicrobial agents

Chiral 1-phenyl-2-propynylamines are important building blocks for the synthesis of antifungal and antiaromatase agents related to bifonazole. In this report, a microwave-assisted Cu(I)-catalyzed 'click chemistry' approach has been employed to easily generate a small library of enantiomerically pure α-[4-(1-substituted)-1,2,3-triazol-4-yl]benzylacetamides starting from racemic propargylamines. These compounds could represent easily accessible intermediates for the synthesis of new antimicrobial agents.