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Z-2-fluoro-3-(4-fluorophenyl)acrylic acid is a chemical compound with the molecular formula C9H6F2O2. It is a derivative of acrylic acid, featuring a fluorine atom at the 2nd position and a 4-fluorophenyl group attached to the 3rd position. This molecule is characterized by its fluorinated aromatic ring, which can influence its electronic properties and reactivity. It is a potential intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and the presence of fluorine atoms, which can enhance the lipophilicity and metabolic stability of the final products. The compound's properties, such as its reactivity, solubility, and potential applications, make it an interesting candidate for further chemical research and development.

94977-49-8

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94977-49-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 94977-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,9,7 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 94977-49:
(7*9)+(6*4)+(5*9)+(4*7)+(3*7)+(2*4)+(1*9)=198
198 % 10 = 8
So 94977-49-8 is a valid CAS Registry Number.

94977-49-8Downstream Products

94977-49-8Relevant academic research and scientific papers

Fluorine-19 Nuclear Magnetic Resonance Study of the Inclusion of Fluoro- and Difluoro-trans-cinnamates by α-Cyclodextrin

Brereton, Ian,Spotswood, Thomas M.,Lincoln, Stephen F.,Williams, Evan H.

, p. 3147 - 3156 (1984)

19F n.m.r. studies of the inclusion of o-, m-, p- and α-fluoro-trans-cinnamates and o, p- and α,p-difluoro-trans-cinnamates by α-cyclodextrin (αCD) have shown that two inclusion equilibria S + αCD S*αCD (K1), S*αCD + αCD S*(αCD)2 (Ksub

Fluorine-containing carboxylic acid compound and preparation method thereof

-

Paragraph 0038-0048; 0082-0085, (2020/09/09)

The invention provides a fluorine-containing carboxylic acid compound and a preparation method and application thereof. The preparation method comprises the steps that a fluorine-containing olefin compound and CO2 react in a solvent in the presence of a c

Copper-Catalyzed Carboxylation of C-F Bonds with CO2

Yan, Si-Shun,Wu, Dong-Shan,Ye, Jian-Heng,Gong, Li,Zeng, Xin,Ran, Chuan-Kun,Gui, Yong-Yuan,Li, Jing,Yu, Da-Gang

, p. 6987 - 6992 (2019/08/26)

An effective Cu-catalyzed selective formal carboxylation of C-F bonds with an atmospheric pressure of CO2 is reported. A variety of gem-difluoroalkenes, gem-difluorodienes, and α-trifluoro-methyl alkenes show high reactivity and selectivity for

An efficient synthesis of (Z)-α-fluorochalcones via the palladium-catalyzed cross-coupling reaction of (Z)-α-fluorocinnamoyl chloride with boronic acids

Eddarir, Said,Kajjout, Mohammed,Rolando, Christian

, p. 1735 - 1738 (2013/03/14)

An efficient synthesis of α-fluorochalcones (1,3-diphenyl-2- fluoroprop-2-en-1-one) based on the Suzuki-Miyaura palladium-catalyzed cross-coupling reaction of arylboronic acids with α-fluorocinnamoyl chlorides in the presence of Cs2CO3/su

A novel reaction of β,β'-dihydroxy acids or esters with vanadium(V) trichloride oxide. New entry to the stereoselective synthesis of α-fluoro- α,β-unsaturated acids and esters

Ishihara, Takashi,Shintani, Atsuhiro,Yamanaka, Hiroki

, p. 4865 - 4868 (2007/10/03)

β,β'-Dihydroxy carboxylic acids and esters, readily prepared from dibromofluoroacetate and aldehydes, underwent deoxygenation, followed by elimination of aldehyde by the action of vanadium(V) trichloride oxide at the reflux temperature of chlorobenzene fo

Preparation et spectres de RMN, H, F et C-13 d'esters α-fluoro-cinnamiques para- et meta-substitues

Elkik, Elias,Francesch, Charlette

, p. 423 - 428 (2007/10/02)

In this publication we present H, F and C-13 NMR spectra of a series of para (11 examples) and meta (7 examples) substituted α-fluoro-Z-cinnamic esters and their corresponding acids.We also discuss the characteristics and scope of the various preparation

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