950188-80-4

Basic information

• Product Name: 1-(5-fluoro-2-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene
• Synonyms: 1-(5-fluoro-2-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene
• CAS NO: 950188-80-4
• Molecular Weight: 251.376
• Mol File: 950188-80-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(5-fluoro-2-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-fluoro-2-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene(950188-80-4)
• EPA Substance Registry System: 1-(5-fluoro-2-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene(950188-80-4)

Safety Data

• Hazardous Substances Data: 950188-80-4(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 22062-53-9 5-fluoro-2-methylbenzaldehyde 
• 75-36-5 acetyl chloride 

Downstream Products

• 1239779-17-9 racemic (2'R,3R,4'S)-4'-[5-chloro-2-(2-methanesulfonylamino-1,1-methyl-2-oxo-ethoxy)pyridin-3-yl]-6-chloro-2'-(5-fluoro-2-methyl-phenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione 
• 1239779-16-8 racemic (2'S,3S,4'R)-4'-[5-chloro-2-(2-methanesulfonylamino-1,1-methyl-2-oxo-ethoxy)pyridin-3-yl]-6-chloro-2'-(5-fluoro-2-methyl-phenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione 
• 1239779-14-6 (2'R,3R,4'S)-6-chloro-4'-[5-chloro-2-(1-hydroxycarbonyl-1-methyl-ethoxy)pyridin-3-yl]-2'-(5-fluoro-2-methyl-phenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione 
• 1239779-13-5 (2'S,3S,4'R)-6-chloro-4'-[5-chloro-2-(1-hydroxycarbonyl-1-methyl-ethoxy)pyridin-3-yl]-2'-(5-fluoro-2-methyl-phenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione 

Relevant articles and documents

SPIROINDOLINONE DERIVATIVE PRODRUGS

There are provided compounds of the formula and pharmaceutically acceptable salts and esters and enantiomers thereof wherein X, Y, V, R1, R2 and R are as described herein. The compounds have utility as antiproliferative agents, especially, as anticancer agents.

SPIROINDOLINONE PYRIDINE DERIVATIVES

There are provided compounds of the formula or a pharmaceutically acceptable salt, ester or enantiomer thereof wherein W, X, Y, V, R1 and R2 are as described herein. The compounds have utility as antiproliferative agents, especially,

SPIROINDOLINONE DERIVATIVES

There are provided spiroindolinone derivatives of the formula and pharmaceutically acceptable salts and esters thereof wherein R1, R2, R3, R4 and R are as herein described. The compounds exhibit anticancer activity.