950651-37-3

Basic information

• Product Name: ethyl {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetate
• Synonyms: ethyl {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetate
• CAS NO: 950651-37-3
• Molecular Weight: 368.356
• Mol File: 950651-37-3.mol

Chemical Properties

• CAS DataBase Reference: ethyl {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetate(950651-37-3)
• EPA Substance Registry System: ethyl {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetate(950651-37-3)

Safety Data

• Hazardous Substances Data: 950651-37-3(Hazardous Substances Data)

Upstream product

• 120-92-3 cyclopentanone 
• 144789-73-1 2-amino-2-[4-(trifluoromethyl)phenyl]acetic acid 
• 390815-48-2 methyl 2-amino-2-[4-(trifluoromethyl)phenyl]acetate hydrochloride 
• 203065-99-0 2-amino-2-(4-(trifluoromethyl)phenyl)acetamide 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 950651-38-4 {2-oxo-3-[4-(trifluoromethyl)phenyl]-1,4-diazaspiro[4.4]non-3-en-1-yl}acetic acid 

Relevant articles and documents

GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS

Compounds of formula (I) or a salt thereof are provided wherein R1, R2, R6, R7, R8, R9 and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture

COMPOUNDS WHICH INHIBIT THE GLYCINE TRANSPORTER AND USES THEREOF

Compounds of formula (I) and salts and solvates thereof are provided: wherein R1 to R8 and n are defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.