95068-01-2

Usage

Common use

Building block in the synthesis of various organic compounds (pharmaceuticals and agrochemicals)

Physical state

Clear, colorless liquid

Odor

Slightly sweet

Solubility

Insoluble in water, soluble in organic solvents

Hazardous nature

Considered a hazardous substance

Handling

Should be handled with care

Application

Primarily used in research and industrial applications

Suitability

Suitable for use in various chemical reactions and processes

Upstream product

• 24398-88-7 ethyl 3-bromobenzoate 
• 7664-93-9 sulfuric acid 
• 108-48-5 2,6-dimethylpyridine 
• 15852-73-0 (3-Bromophenyl)methanol 
• 64-17-5 ethanol 
• 823-78-9 meta-bromobenzyl bromide 
• 3132-99-8 m-bromobenzoic aldehyde 
• 2031-62-1 diethoxymethylane 

Downstream Products

• 443147-13-5 2-(S)-hydroxy-3-(3-ethoxymethylphenyl)propan-1-ol trityl ether 
• 443147-15-7 2-(S)-hydroxy-3-(3-ethoxymethylphenyl)propan-1-ol 
• 443147-27-1 3-(S)-hydroxy-4-(3-ethoxymethylphenyl)-1-butyne 
• 443147-17-9 2-(S)-1-acetoxy-3-(3-ethoxymethylphenyl)propan-2-ol 
• 443147-23-7 2-(S)-tetrahydropyranyloxy-3-(3-ethoxymethylphenyl)propan-1-al 
• 443147-21-5 2-(S)-tetrahydropyranyloxy-3-(3-ethoxymethylphenyl)propan-1-ol 
• 443147-25-9 3-(S)-tetrahydropyranyloxy-4-(3-ethoxymethylphenyl)-1-butyne 
• 443147-29-3 3-(S)-t-butyldimethylsilyloxy-4-(3-ethoxymethylphenyl)-1-butyne 
• 443147-31-7 3-(S)-t-butyldimethylsilyloxy-1-iodo-4-(3-ethoxymethylphenyl)-1-butene 
• 443147-33-9 1,1-dibromo-3-(S)-tetrahydropyranyloxy-4-(3-ethoxymethylphenyl)-1-butene 
• 443147-19-1 1-acetoxy-3-(3-ethoxymethylphenyl)-2-(S)-tetrahydropyranyloxypropane 
• 443147-41-9 7-{(1R,2R,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl)-3-hydroxy-but-1-enyl]-3-hydroxy-5-oxo-cyclopentyl}-heptanoic acid methyl ester 
• 443147-37-3 (Z)-7-{(1R,2R,3R)-2-[(E)-(S)-4-(3-Ethoxymethyl-phenyl)-3-hydroxy-but-1-enyl]-3-hydroxy-5-oxo-cyclopentyl}-hept-5-enoic acid methyl ester 
• 261772-73-0 (Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(3-ethoxymethyl-phenyl)-3-hydroxy-but-1-enyl]-3-hydroxy-cyclopentyl}-hept-5-enoic acid methyl ester 

Relevant academic research and scientific papers

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

Reductive etherification of aldehydes photocatalyzed by dicarbonyl pentamethylcyclopentadienyl iron complexes

The reductive etherification of aldehydes can be performed by the reaction with dialkylmethylsilanes in the presence of new iron(II) piano-stool catalysts of general formula Cp*Fe(CO)2Ar (Cp * = η5-C5Me5; Ar = Ph, 4-C6H4OCH3, 4-C6H4CH 3, Fc). This transformation is promoted by UV light and affords a simple route for the preparation of unsymmetrical alkyl ethers.

New method for the synthesis of benzyl alkyl ethers mediated by FeSO 4

The synthesis of benzyl alkyl ethers from benzyl bromides and alcohols using FeSO4 as a recoverable and reusable mediator has been described without use of base and cosolvent under mild conditions.

C4 -amide substituted compounds and their use as therapeutic agents

The invention provides certain 5 and/or 8 substituted benzopyran, pyranopyridine or tetrahydroquinaline compounds having C4 -amide substituent and processes for making them. The compounds described are useful in treating and/or preventing certain disorders.