950747-16-7Relevant academic research and scientific papers
Asymmetric total synthesis of (-)-mangiferaelactone by using an appropriately substituted thiophene as a masked synthon for C-alkyl glycoside
Kumar, Rajan,Rej, Rohan Kalyan,Nanda, Samik
, p. 751 - 759 (2015/07/15)
Abstract Asymmetric total synthesis of naturally occurring nonenolide (-)-mangiferaelactone was attempted through RCAM (ring closing alkyne metathesis) reaction. As the attempted RCAM reaction failed, the synthesis was finally achieved by successful explo
First total synthesis of modiolide A, based on the whole-cell yeast-catalyzed asymmetric reduction of a propargyl ketone
Matsuda, Masaaki,Yamazaki, Takahiro,Fuhshuku, Ken-ichi,Sugai, Takeshi
, p. 8752 - 8760 (2008/02/10)
While the first total synthesis of modiolide A (1a), a 10-membered ring lactone with a marine-origin was achieved, an important chiral building block for constructing the chirality at C-4 in 1a, (S)-6-[(4-methoxybenzyl)oxy]-1-trimethylsilyl-1-hexyn-3-ol (
New marine prostanoids, preclavulone lactones, from the Okinawan soft coral Clavularia viridis
Iwashima, Makoto,Watanabe, Kinzo,Iguchi, Kazuo
, p. 8319 - 8322 (2007/10/03)
Two new marine prostanoids, preclavulone lactones I (1) and II (2) were isolated from the Okinawan soft coral, Clavularia viridis. Their structures were determined based on spectroscopic analysis and chemical synthesis from (S)-malic acid. Preclavulone lactones with side chains having absolute configurations opposite to those of mammalian prostanoids could be recognized as key intermediates in biosynthesis of clavulones.
