950849-49-7Relevant academic research and scientific papers
Intramolecular Schmidt reaction of acyl chlorides with alkyl azides: Rapid access to fused polycyclic nitrogen-containing heterocycles via a multistep one-pot transformation
Gu, Peiming,Kang, Xiao-Yan,Sun, Jian,Wang, Bao-Juan,Yi, Ming,Li, Xue-Qiang,Xue, Ping,Li, Rui
supporting information, p. 5796 - 5799 (2013/01/15)
The first intramolecular Schmidt reaction of acyl chlorides with alkyl azides has been developed. In this one-pot conversion, an ω-azido hydrocinnamic acid is converted to a tricyclic lactam. The most important feature of the process is the efficiency in bond formation (one bond broken and three new bonds created) and ring construction (two new rings formed).
Intramolecular and intermolecular Schmidt reactions of alkyl azides with aldehydes
Lee, Huey-Lih,Aubé, Jeffrey
, p. 9007 - 9015 (2008/02/10)
Despite recent advances in the use of alkyl azides in ring expansion reactions of ketones, there has been little work done on the corresponding chemistry of aldehydes. In the present study, the Lewis acid-promoted reactions of alkyl azides with aldehydes
