950918-52-2

Upstream product

• 950918-49-7 (2-fluoro-pyridin-4-yl)-(2-methoxy-phenyl)-methanol 
• 22282-70-8 2-fluoro-4-iodopyridine 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 950918-55-5 (2-amino-pyridin-4-yl)-(2-methoxy-phenyl)-methanone 
• 950918-64-6 [4-(tert-butoxycarbonylamino-imino-methyl)-benzyl]-{4-[(tert-butyl-dimethyl-silanyloxy)-(2-methoxy-phenyl)-methyl]-pyridin-2-yl}-carbamic acid tert-butyl ester 
• 950918-61-3 {4-[(tert-butyl-dimethyl-silanyloxy)-(2-methoxy-phenyl)-methyl]pyridin-2-yl}-(4-cyano-benzyl)-carbamic acid tert-butyl ester 
• 950918-58-8 (4-cyano-benzyl)-[4-(2-methoxy-benzoyl)-pyridin-2-yl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold

A series of 2,4-disubstituted pyridine derivatives has been designed, synthesised and evaluated as thrombin inhibitors. A Grignard exchange reaction was used to introduce various benzoyl substituents in position 4 of the pyridine ring, where they serve as