950918-54-4

Basic information

• Product Name: (2-aminoo-pyridin-4-yl)-phenyl-methanone
• Synonyms: (2-aminoo-pyridin-4-yl)-phenyl-methanone
• CAS NO: 950918-54-4
• Molecular Weight: 198.224
• Mol File: 950918-54-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-aminoo-pyridin-4-yl)-phenyl-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-aminoo-pyridin-4-yl)-phenyl-methanone(950918-54-4)
• EPA Substance Registry System: (2-aminoo-pyridin-4-yl)-phenyl-methanone(950918-54-4)

Safety Data

• Hazardous Substances Data: 950918-54-4(Hazardous Substances Data)

Upstream product

• 950918-51-1 (2-fluoro-pyridin-4-yl)-phenyl-methanone 
• 950918-48-6 (2-fluoro-pyridin-4-yl)-phenyl-methanol 
• 100-52-7 benzaldehyde 
• 22282-70-8 2-fluoro-4-iodopyridine 
• 14548-46-0 4-Benzoylpyridine 
• 14178-29-1 (1-oxidopyridin-4-yl) (phenyl)methanone 

Downstream Products

• 950918-57-7 (4-benzoyl-pyridin-2-yl)-(4-cyano-benzyl)-carbamic acid tert-butyl ester 
• 950918-60-2 {4-[(tert-butyl-dimethyl-silanyloxy)-phenyl-methyl]-pyridin-2-yl}-(4-cyano-benzyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Reaction of Pyridine-N-Oxides with Tertiary sp2-N-Nucleophiles: An Efficient Synthesis of Precursors for N-(Pyrid-2-yl)-Substituted N-Heterocyclic Carbenes

N-(Pyrid-2-yl)-substituted azolium and pyridinium salts, precursors for hybrid NHC-containing ligands, were obtained with excellent regioselectivity, employing a deoxygenative CH-functionalization of pyridine-N-oxides with substituted imidazoles, thiazoles, and pyridine. Unlike the traditional SNAr-based methods, this approach provides high yields for substrates bearing substituents of different electronic nature. The utility of azolium and pyridinium salts thus prepared was also highlighted by the synthesis of pyridyl-substituted imidazolyl-2-thione, benzodiazepine as well as 2-aminopyridines.