95095-11-7

Basic information

• Product Name: 4,10-Dioxo-3-methyl-2-phenyl-4H,10H-benzo<1,2-b:3,4-b'>dipyran-8-carboxylic acid
• CAS NO: 95095-11-7
• Molecular Weight: 348.312
• Mol File: 95095-11-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,10-Dioxo-3-methyl-2-phenyl-4H,10H-benzo<1,2-b:3,4-b'>dipyran-8-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,10-Dioxo-3-methyl-2-phenyl-4H,10H-benzo<1,2-b:3,4-b'>dipyran-8-carboxylic acid(95095-11-7)
• EPA Substance Registry System: 4,10-Dioxo-3-methyl-2-phenyl-4H,10H-benzo<1,2-b:3,4-b'>dipyran-8-carboxylic acid(95095-11-7)

Safety Data

• Hazardous Substances Data: 95095-11-7(Hazardous Substances Data)

Upstream product

• 95095-00-4 (Z)-2-(3-Methyl-4-oxo-2-phenyl-4H-chromen-7-yloxy)-but-2-enedioic acid dimethyl ester 
• 18651-15-5 7-hydroxy-3-methylflavone 

Downstream Products

• 95095-14-0 Methyl 4,10-dioxo-3-methyl-2-phenyl-4H,10H-benzo<1,2-b:3,4-b'>dipyran-8-carboxylate 

Relevant articles and documents

Analogues of Disodium Cromoglycate as Antiallergic Agents: Part I - Synthesis of Some Chromone Carboxylic Acids: 4,10-Dioxo-2-phenyl-4H,10H-benzodipyran-8-carboxylic Acids

Novel chromone-2-carboxylic acid derivatives, 4,10-dioxo-2-phenyl-4H,10H-benzodipyran-8-carboxylic acids (VIIa-c), have been synthesised by the condensation of appropriate 7-hydroxyflavones with dimethyl acetylenedicarboxylate (DMAD) and cyclisation of the resulting hydrolysed adduct mixtures (Va-c) with conc.sulphuric acid.The structures of these acids have been assigned on the basis of analytical and spectral data, and confirmed by their unambiguous synthesis.Among these compouds, 4,10-dioxo-3-methyl-2-phenyl-4H,10H-benzodipyran-8-carboxylic acid (VIIb) possess high antiallergic activity equivalent to that of disodium cromoglycate (DSCG) when tested by passive peritonial anaphylaxis method in rats.