951658-86-9Relevant academic research and scientific papers
Inhibitory evaluation of sulfonamide chalcones on β-secretase and acylcholinesterase
Kang, Jae Eun,Cho, Jung Keun,Curtis-Long, Marcus J.,Ryu, Hyung Won,Kim, Jin Hyo,Kim, Hye Jin,Yuk, Heung Joo,Kim, Dae Wook,Park, Ki Hun
, p. 140 - 153 (2013/04/23)
The action of β-secretase (BACE1) is strongly correlated with the onset of Alzheimer's disease (AD). Aminochalcone derivatives were examined for their ability to inhibit BACE1. Parent aminochalcones showed two digit micromolar IC50s against BACE1. Potency
Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone
Seo, Woo Duck,Ryu, Young Bae,Curtis-Long, Marcus J.,Lee, Chan Woo,Ryu, Hyung Won,Jang, Ki Chang,Park, Ki Hun
experimental part, p. 2010 - 2017 (2010/07/04)
The 4′-(p-toluenesulfonylamino)-4-hydroxychalcone (TSAHC), which bears inhibitory chemotypes for both α-glucosidase and tyrosinase, was evaluated for tyrosinase activity and depigmenting ability relative to compounds designed to only target tyrosianse act
