951894-85-2

Upstream product

• 120-80-9 benzene-1,2-diol 
• 4739-94-0 ethyl 2,3-dihydro-1,4-benzodioxin-2-carboxylate 
• 90557-92-9 2,3-dihydro-1,4-benzodioxane-2-carbohydrazide 
• 100-09-4 4-methoxybenzoic acid 

Relevant academic research and scientific papers

Synthesis and antihepatotoxic activity of 2-(substituted-phenyl)-5-(2,3- dihydro-1,4-benzodioxane-2-yl)-1,3,4-oxadiazole derivatives

Novel 1,3,4-oxadizole derivatives containing the 1,4-dioxane ring system were synthesised starting from 2,3-dihydro-1,4-benzodioxane-2-carbohydrazide. The synthesised compounds were evaluated for antihepatotoxic activity against CCl4-induced hepatotoxicity in rats. Some compounds demonstrated a significant antihepatotoxic activity comparable to the standard drug Silymarin.