95192-69-1

Upstream product

• 2065-28-3 methyl 5-methyl-3-phenylisoxazole-4-carboxylate 
• 70272-01-4 methyl 3-amino-3-phenylacrylate 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 1136-45-4 5-methyl-3-phenylisoxazol-4-carboxylic acid 

Downstream Products

• 21905-49-7 5-methyl-3-phenyl-isothiazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

ISOTHIAZOLE-PYRIDINE DERIVATIVES AS MODULATORS OF HIF (HYPOXIA INDUCIBLE FACTOR) ACTIVITY

The present invention relates to novel compounds according to Formula I or II, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF). Formula (I) or (II).

E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME

E-isomeric ?-(hetero) aromatically substituted acylaminoacrylates are of great economic interest since with them, by means of hydration, precursors of appropriately substituted (?-amino acids can be prepared and, by doing so, lead to higher enantio-select