95201-98-2

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 4-CHLORO-3-HYDROXY-5-METHOXYTHIOPHENE-2-CARBOXYLATE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs due to its unique molecular structure and functional groups.
Used in Agrochemical Industry:
In the agrochemical sector, METHYL 4-CHLORO-3-HYDROXY-5-METHOXYTHIOPHENE-2-CARBOXYLATE serves as an intermediate in the production of agrochemicals, potentially enhancing crop protection and yield through its incorporation into active ingredients.
Used in Dye and Pigment Production:
METHYL 4-CHLORO-3-HYDROXY-5-METHOXYTHIOPHENE-2-CARBOXYLATE is utilized in the creation of dyes and pigments, capitalizing on its color-producing properties to meet the demands of various industries that require coloring agents for their products.

InChI:InChI=1/C7H7ClO4S/c1-11-6(10)5-4(9)3(8)7(12-2)13-5/h9H,1-2H3

Upstream product

• 67-56-1 methanol 
• 65449-58-3 2,4-dichloro-2-methoxycarbonyl-3-oxo-2,3-dihydrothiophene 
• 5118-06-9 methyl 3-hydroxy-2-thiophenecarboxylate 

Downstream Products

• 95202-24-7 2-benzylidene-4-chloro-5-methoxythiophen-3(2H)-one 
• 95202-22-5 2-benzylidene-5-methoxythiophen-3(2H)-one 
• 95202-14-5 4-Chloro-5-methoxy-thiophen-3-one 

Relevant academic research and scientific papers

Organic compounds and their use as pharmaceuticals

Compounds of the following formula have pharmacutical properties: STR1 in which R1 and R2 independently are hydrogen, halo, nitro, amino, C2-5 acylamino, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl, N-substituted heterocyclyl, optionally substituted phenyl, optionally substituted phenylthio, optionally substituted phenylsulphonyl or optionally substituted phenylsulphonamido, or R1 and R2 together form a C3-5 alkylene bridge, R3 is C1-4 alkyl or C2-4 alkenyl, and X is (i) --(CH2)n N(R4)2 where each R4 independently is C1-4 alkyl, C2-4 alkenyl or optionally substituted C6 H5 CH2 --, and n is 1, 2 or 3, or (ii) a 5- to 8-membered alicyclic group containing one or two nitrogen atoms and directly attached to the amido nitrogen or attached by a C1-3 alkylene chain; and salts thereof.

Reactions with Methyl 3-Hydroxythiophene-2-carboxylate. Part 2. A New Route to Mono- and Di-alkyl Ethers of Thiotetronic and α-Halogenothiotetronic Acids

Methyl 2-chloro-3-oxo-2,3-dihydrothiophene-2-carboxylates (2), obtained from methyl 3-hydroxythiophene-2-carboxylate by straightforward halogenation, added alcohols and then lost hydrogen chloride at room temperature to yield thiophene-2,4-diols (4).Succe