95215-03-5

Upstream product

• 29114-93-0 meso-tetra(m-methoxyphenyl)porphyrin 
• 6046-93-1 copper(II) acetate monohydrate 

Downstream Products

• 95212-95-6 [2-nitro-5,10,15,20-tetrakis(3-methoxyphenyl)porphyrinato]copper(II) 
• 1412456-51-9 [2-amino-3-nitro-5,10,15,20-tetrakis(3-methoxyphenyl)porphyrinato]copper(II) 
• 95212-95-6 (2-nitro-5,10,15,20-tetra-m-methoxyphenylporphyrinato)copper(II) 

Relevant academic research and scientific papers

Direct β-amination reaction in porphyrin systems - A simple route to compounds containing two nitrogen substituents at both β-positions of the same pyrrole unit

The direct β-amination of porphyrin derivatives is described. 2-Nitro-meso-tetraarylporphyrins (zinc and copper complexes) react with N,N,N-trimethylhydrazinium iodide (TMHI) in the presence of a base (KOH/DMSO system, ca 70-80 °C) to give products of nucleophilic aromatic substitution of hydrogen. In this process, the nucleophilic replacement of a H-atom by an NH2 group takes place. The products obtained, bearing two neighbouring nitrogen substituents on the same pyrrole ring, are valuable intermediates for various synthetic uses.