952677-55-3

Upstream product

• 142945-21-9 (2R,3R,5R,6S)-2-(3-Benzyloxy-propyl)-7-(tert-butyl-diphenyl-silanyloxy)-5-methoxy-3-methoxymethoxy-6-methyl-heptan-1-ol 
• 142945-20-8 4-Benzyl-3-[(2S,3R,5R,6S)-2-(3-benzyloxy-propyl)-7-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-5-methoxy-6-methyl-heptanoyl]-oxazolidin-2-one 
• 142945-18-4 (5-Benzyloxy-3-methoxy-2-(methyl)pentyloxy)-tert-butyldiphenylsilane 
• 301230-09-1 5-Benzyloxy-1-(tert-butyldiphenylsilanyloxy)-2-methylpentane-3-ol 
• 142954-43-6 5-(tert-Butyldiphenylsilanyloxy)-3-methoxy-4-methylpentanal 
• 301230-10-4 (3R,4S)-5-(tert-butyldiphenylsilyloxy)-3-methoxy-4-methylpentan-1-ol 
• 105560-79-0 5-Benzyloxy-2-methylpentane-1,3-diol 
• 89923-31-9 (E)-5-(benzyloxy)pent-2-en-1-ol 
• 89956-14-9 [3-(2-Benzyloxyethyl)oxiran-2-yl]methanol 

Downstream Products

• 142945-16-2 (2R,3R,5R,6S)-9-Benzyloxy-3-methoxy-5-methoxymethoxy-2,6-dimethyl-nonanal 
• 142945-24-2 (E)-(4R,5R,9S,10R,12R,13S)-16-Benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-4,10-dimethoxy-12-methoxymethoxy-5,9,13-trimethyl-hexadec-7-en-6-one 

Relevant academic research and scientific papers

Synthetic Studies towards Halichondramides, and Related Novel tris-Oxazole Containing Macrolides from Marine Organisms. A Concise Route to the Keto-triol Formyl Enamine Moiety.

A synthesis of the keto-triol formyl enamine moiety (3) in the marine metabolite halichondramide (1) is described.The synthesis features judicious application of the Evans chiral aldol protocol in combination with the controlled ring opening of chiral α-e