95273-01-1

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-6,8-dimethyl-
• CAS NO: 95273-01-1
• Molecular Formula: C18H18O5
• Molecular Weight: 314.338
• Mol File: 95273-01-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-6,8-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-6,8-dimethyl-(95273-01-1)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-6,8-dimethyl-(95273-01-1)

Safety Data

• Hazardous Substances Data: 95273-01-1(Hazardous Substances Data)

Upstream product

• 4463-02-9 2,4-dimethylbenzene-1,3,5-triol 
• 42996-84-9 p-methoxycinnamoyl chloride 
• 34446-64-5 (E)-3-(4-methoxyphenyl)propenoyl chloride 
• 13383-63-6 1-(2,4,6-trihydroxy-3,5-dimethylphenyl)ethan-1-one 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1008101-25-4 matteucinolchalcone triacetate 
• 117820-79-8 matteucinol diacetate 
• 94451-48-6 syzalterin 
• 1352409-55-2 5-acetoxy-2,3-dihydro-7-dimethoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4H-1-benzopyran-4-one 
• 1352409-59-6 5-hydroxy-7,4'-dimethoxy-6,8-dimethylflavan 
• 910883-18-0 matteucinol diacetate 
• 101395-13-5 2,3-dihydro-5,7-dimethoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4H-1-benzopyran-4-one 
• 110048-94-7 2,3-dihydro-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4H-1-benzopyran-4-one 
• 90145-57-6 5,7-dihydroxy-4'-methoxy-6,8-dimethylanthocyanidin 
• 90145-58-7 4,5,7-trihydroxy-4'-methoxy-6,8-dimethylflavan 

Relevant articles and documents

Synthesis and biological activity of flavanone derivatives

A series of new flavanone derivatives of farrerol was synthesized by a convenient method. The in vitro anti-tumor activity of these compounds was evaluated against human Bel-7402, HL-60, BGC-823 and KB cell lines, the protein tyrosine kinase (PTK) inhibitor activity was also tested. Their cytoprotective activity was tested using hydrogen peroxide (H2O2)-induced injury in human umbilical vein endothelial cells. Their in vitro anti-atherosclerosis activity was tested on vascular smooth muscle cells by the MTT method using tetrandrine as a positive contrast drug. The structures of all compounds synthesized were confirmed by 1H, 13C NMR and ESI-MS. Most of the compounds exhibited good pharmacological activity and the preliminary structure-activity relationships were described.