95337-70-5 Usage
Description
4-(2,5-DIMETHYL-1H-PYRROL-1-YL)BENZALDEHYDE, also known as Tropinone, is a chemical compound characterized by its molecular formula C14H15NO. It is a white to off-white powder that serves as a crucial building block in the synthesis of various organic compounds and pharmaceuticals. Tropinone is recognized for its role as a key intermediate in the production of atropine, a medication with applications in treating nerve agent and pesticide poisonings, as well as in medical procedures requiring reduced salivation and respiratory secretions.
Uses
Used in Pharmaceutical Industry:
4-(2,5-DIMETHYL-1H-PYRROL-1-YL)BENZALDEHYDE is used as a key intermediate for the synthesis of atropine, a medication that is employed to counteract the effects of certain nerve agents and pesticide poisonings. It is also utilized to manage excessive salivation and respiratory secretions during surgical procedures.
Used in the Synthesis of Anticholinergic Drugs:
In the pharmaceutical industry, 4-(2,5-DIMETHYL-1H-PYRROL-1-YL)BENZALDEHYDE is used as a precursor in the production of other drugs that exhibit anticholinergic effects, which are beneficial in treating a variety of conditions by blocking the action of acetylcholine, a neurotransmitter.
Used in the Production of Cocaine:
4-(2,5-DIMETHYL-1H-PYRROL-1-YL)BENZALDEHYDE is also utilized as a precursor in the chemical synthesis of cocaine, highlighting its importance in the creation of substances with both medicinal and illicit uses.
Used in the Chemical Industry:
Beyond its pharmaceutical applications, 4-(2,5-DIMETHYL-1H-PYRROL-1-YL)BENZALDEHYDE is used as a building block in the chemical industry for the synthesis of a wide range of biologically active molecules, contributing to the development of new compounds with potential therapeutic and commercial value.
Check Digit Verification of cas no
The CAS Registry Mumber 95337-70-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,3,3 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 95337-70:
(7*9)+(6*5)+(5*3)+(4*3)+(3*7)+(2*7)+(1*0)=155
155 % 10 = 5
So 95337-70-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO/c1-10-3-4-11(2)14(10)13-7-5-12(9-15)6-8-13/h3-9H,1-2H3
95337-70-5Relevant articles and documents
One-pot synthesis of: N -substituted pyrroles from nitro compounds and 2,5-hexadione over a heterogeneous cobalt catalyst
Gong, Zheng,Lei, Yu,Zhou, Peng,Zhang, Zehui
, p. 10613 - 10618 (2017/10/05)
In this study, the one-pot heterocyclization of nitro compounds with 2,5-hexadione was studied for the synthesis of N-substituted pyrroles via a Paal-Knorr condensation process. The heterogeneous cobalt-nitrogen catalyst (Co-Nx/C-800-AT) was found to be active for this reaction with formic acid. Formic acid served as a hydrogen donor for the transfer hydrogenation, and also acted as an acid catalyst. More importantly, this method was tolerant of other functional groups, and hence various N-substituted pyrroles were produced with good to excellent yields. The Co-Nx/C-800-AT catalyst was highly stable, and could be reused several times without loss of its catalytic activity.