95412-14-9Relevant academic research and scientific papers
Preparation and reactions of 3-and 4-tributylstannyl-2-(5H)-furanones: Preparation of aryl furanones
Hollingworth, Gregory J.,Sweeney
, p. 7049 - 7052 (2007/10/02)
3- and 4-trialkylstannylfuranones (2) and (3) have been prepared by an interesting desulphurative stannylation reaction; 3- and 4-substituted 2-(5H)-Furanones (12) and (13) may be prepared via palladium-catalysed cross coupling of (2) and (3) with aryl iodides.
INVESTIGATIONS IN THE SERIES OF SUBSTITUTED BUTAN- AND BUTENOLIDES. III. SYNTHESIS OF ARYLBUTAN- AND ARYLBUTENOLIDES AND THEIR PROPERTIES
Chellar, N. S.,Badovskaya, L. A.,Ignatenko, A. V.
, p. 1775 - 1779 (2007/10/02)
A new method was developed for the synthesis of 2-aryl- and 3-aryl-2-buten-4-olides by the arylation of 2-buten-4-olide with diazonium halides in the presence of cupric chloride as catalyst.The intermediate products of the reaction are the corresponding arylchlorobutanolides. 4-R-Methylene-3-aryl-2-buten-4-olides and 4-hydroxy-3-aryl-2-butenamides were obtained in the reaction of 3-aryl-2-buten-4-olides with aldehydes and primary aliphatic amines respectively.Some of the synthesized compounds have antimicrobial and growth-stimulant activity.
