95459-73-7Relevant academic research and scientific papers
Benzoic acid derivative as well as preparation method and medicinal application thereof
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Paragraph 0048; 0053-0055, (2021/09/21)
The invention discloses a benzoic acid derivative as well as a preparation method and a pharmaceutical application thereof, and belongs to the technical field of medicines. The invention specifically discloses a benzoic acid derivative represented by a co
An efficient synthesis of benzofurans and their application in the preparation of natural products of the genus Calea
Del Carmen Cruz, María,Tamariz, Joaquín
, p. 10061 - 10072 (2007/10/03)
The intramolecular cyclization of the β-substituted olefins methyl 2-aryloxy-3-dimethylaminopropenoates 3a-3f catalyzed by Lewis acids leads to a short and novel synthesis of benzofurans 2a-2f. When the olefins 4-dimethylamino-3-aryloxy-3-buten-2-ones 4a-4f were used, the cyclization process was faster and provided the corresponding substituted 2-acetylbenzofurans 1a-1f. Among the latter, naturally occurring compounds calebertin (1a), caleprunin A (1b), and caleprunin B (1c) were prepared in good overall yields. These benzofurans were also obtained by direct treatment under MW irradiation of the precursors 1-aryloxypropan-2-ones 7a-7c with DMFDMA, followed by addition of the catalyst, resulting in a route that was one step shorter.
Captodative olefins: Methyl 2-aryloxy-3-dimethyl-aminopropenoates and their application in a new synthesis of benzofurans
Cruz, María Del Carmen,Tamariz, Joaquín
, p. 2377 - 2380 (2007/10/03)
The β-substituted captodative olefins methyl 2-aryloxy-3- dimethylaminopropenoates 4a-h were synthesized, via aminomethylenation of the corresponding 2-phenoxyacetic esters 9a-h. Lewis acid promoted intramolecular cyclization of alkenes 4 led to benzofurans 7a-h, in an efficient synthetic approach to the benzofuran frame.
Phenylacetamide derivatives
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, (2008/06/13)
A phenylacetamide derivative of formula (I) have potent analgesic and anti-inflammatory activities and exhibit less irritability and toxicity: STR1 wherein, X, Y, W, n, m and Ar are as defined in the specification.
TRIOXATRUXENES: A NEW FAMILY OF DISC-LIKE MESOGENS WITH A COMPLEX POLYMORPHISM
Destrade, Christian,Tinh, Nguyen Huu,Mamlok, Lonka,Malthete, Jacques
, p. 139 - 150 (2007/10/02)
A homologous series of hexa-n-alkanoyloxytrioxatruxenes has been prepared with n=7 to n=15 in order to check the influence upon the mesomorphic properities exerted by the substitution of the three methylenes of the truxene core by oxygen atoms.Interphase
