95479-52-0

Basic information

• Product Name: 2-Benzothiazolecarbonitrile, 3-(4-chlorobenzoyl)-2,3-dihydro-
• CAS NO: 95479-52-0
• Molecular Formula: C15H9ClN2OS
• Molecular Weight: 300.768
• Mol File: 95479-52-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Benzothiazolecarbonitrile, 3-(4-chlorobenzoyl)-2,3-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazolecarbonitrile, 3-(4-chlorobenzoyl)-2,3-dihydro-(95479-52-0)
• EPA Substance Registry System: 2-Benzothiazolecarbonitrile, 3-(4-chlorobenzoyl)-2,3-dihydro-(95479-52-0)

Safety Data

• Hazardous Substances Data: 95479-52-0(Hazardous Substances Data)

Upstream product

• 95479-50-8 2,3-dihydro-3-(4-methylbenzoyl)-2-benzothiazolecarbonitrile 
• 113372-40-0 2,3-dihydro-3-methoxycarbonyl-2-benzothiazolecarbonitrile 
• 95-16-9 1,3-Benzothiazole 
• 7677-24-9 trimethylsilyl cyanide 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 1383256-44-7 [1-(4-chlorophenyl)benzo[d]pyrrolo[2,1-b]thiazole-2,3-diyl]bis(methylene)bis(iso-propylcarbamate) 
• 1383256-34-5 (1-(4-chlorophenyl)benzo[d]pyrrolo[2,1-b]thiazole-2,3-diyl)bis(methylene)bis(ethyl-carbamate) 
• 1383256-24-3 [1-(4-chlorophenyl)benzo[d]pyrrolo[2,1-b]thiazole-2,3-diyl]dimethanol 
• 1383256-14-1 dimethyl 1-(4-chlorophenyl)benzo[d]pyrrolo[2,1-b]thiazole-2,3-dicarboxylate 

Relevant articles and documents

SYNTHESIS OF 4H-BENZO[D]PYRROLO[1,2-A]THIAZOLES AND INDOLIZINO[6,7-b]INDOLE DERIVATIVES AND THEIR USE AS ANTITUMOR THERAPEUTIC AGENTS

The present invention provides a series of 2,3-bis(hydroxymethyl)-4H-benzo[d]pyrrolo-[1,2-a]thiazoles and 1,2-bis(hydroxymethyl)indolizino[6,7-b]indole derivatives and their bis(alkylcarbamates) derivatives. These derivatives were designed as bi-functiona

Reissert Compound Formation with Fused Five-Membered Ring Heterocycles

Reissert compounds have been prepared in high yield from benzothiazole by use of trimethylsilyl cyanide as source of cyanide in a single phase system.Analogues have been made from benzoxazole, indazole and 1-methylindazole but the method was unsuccessful with 1,2-benzisoxazole and pyrazole.Conjugate base alkylation followed by removal of the Reissert grouping provides a route to 2-alkylbenzothiazoles and -benzoxazoles, and 3-alkylated indazoles.Efficient access to pyridobenzothiazole and benzothiazoloisoquinoline derivatives results from appropriate intramolecular cyclisations.A crystal structure determination of 3-benzoyl-2,3-dihydro-2-benzothiazolecarbonitrile is reported.